Here is the detailed overview of Lenalidomide Capsule 25 mg with icons:
💊 Lenalidomide Capsule 25 mg
🧪 Nature / Drug Class
🔹 Anticancer / Immunomodulatory Drug (IMiD)
🔹 Structural derivative of thalidomide
🔹 Exerts anti-tumor, anti-angiogenic, and immune-enhancing effects
🩺 Purpose / Indications
✅ Approved for the treatment of:
- 🧬 Multiple Myeloma (in combination therapy)
- 🧫 Myelodysplastic Syndromes (MDS) – 5q deletion
- 🧠 Mantle Cell Lymphoma (MCL) – relapsed/refractory
- 🦠 Follicular and Marginal Zone Lymphomas (with rituximab)
- 📋 Off-label: Chronic Lymphocytic Leukemia (CLL), other lymphomas
⚙️ Advantages
✔️ Oral administration – convenient for outpatient use
✔️ Effective in relapsed/refractory multiple myeloma
✔️ Combined with dexamethasone or proteasome inhibitors
✔️ Lower incidence of peripheral neuropathy than thalidomide
📦 Common Packaging
📦 Capsules: 25 mg (also available in 2.5, 5, 10, 15 mg)
💊 Packed in blister packs
🔒 Distributed through restricted access program due to teratogenicity
⚠️ Patient Advice / Precautions
🚨 Highly teratogenic – strict pregnancy prevention required
📋 Dispensed under REMS or equivalent safety program
💊 Usually taken once daily for 21 days of a 28-day cycle
🧪 Monitor regularly for:
- Complete Blood Counts (CBC)
- Renal and liver function
- Signs of blood clots, infections, or tumor flare
💉 May require antithrombotic prophylaxis
⚠️ Use with caution in renal impairment – dose adjustments needed
🧊 Storage
🌡️ Store at 20–25°C (Room Temperature)
🧴 Keep capsules in original packaging
🧒 Keep out of reach of children