Formulation: A sterile, clear, colorless to pale yellow solution of enoxaparin sodium, a low molecular weight heparin (LMWH), supplied in a pre-filled syringe.
Concentration: Each 0.4 mL syringe contains 40 milligrams (mg) of enoxaparin, designed for subcutaneous injection.
Advantages
Effective Clot Prevention/Treatment: Highly effective in preventing new blood clots and treating existing ones, aiding the body’s natural breakdown process.
Predictable Anticoagulation: Offers a more consistent anticoagulant response compared to unfractionated heparin, often requiring less routine laboratory monitoring.
Uses
DVT/PE Prophylaxis: Used to prevent Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE) in patients undergoing surgery or acutely ill with reduced mobility.
Acute Coronary Syndromes: Employed in the management of conditions like Unstable Angina (UA) and Non-ST-elevation Myocardial Infarction (NSTEMI).
Nature
Low Molecular Weight Heparin (LMWH): Enoxaparin is a derivative of unfractionated heparin, characterized by its smaller molecular size.
Mechanism of Action: Primarily acts by potentiating antithrombin III, leading to a selective and potent inhibition of Factor Xa in the coagulation cascade, thus preventing clot formation.
Storage
Temperature: Store at controlled room temperature, typically between 20∘C to 25∘C (68∘F to 77∘F).
Protection & Handling: Keep in the original carton to protect from light; do not freeze; designed for single-dose use and should be discarded after injection.
