Here is the detailed pharmaceutical description for both Vitamin A Oral Liquid (100,000 IU/mL) and Vitamin A Injection (50,000 IU/mL):
🧴 Vitamin A Oral Liquid – 100,000 IU/mL
✅ DESCRIPTION
A fat-soluble vitamin preparation in oral liquid form, used for prevention and treatment of Vitamin A deficiency, especially in pediatric and malnourished populations.
⚖️ COMPOSITION
- Each 1 mL contains Vitamin A Palmitate or Acetate equivalent to 100,000 IU of Vitamin A.
- Typically formulated in oil base (like refined vegetable oil) with or without flavoring for pediatric use.
📌 USES
- Prevention and treatment of Vitamin A deficiency
- Management of xerophthalmia, night blindness, and immune deficiency
- Measles in children (WHO guidelines)
- Mass supplementation in public health programs
🌟 ADVANTAGES
- Suitable for infants and young children who cannot swallow tablets
- Easily measurable dropper or spoon dosing
- Effective for rapid replenishment
⚠️ PRECAUTIONS
- Do not exceed prescribed dosage — risk of toxicity
- Monitor for signs of hypervitaminosis A, especially in long-term use
- Use with caution in hepatic impairment
💊 DOSAGE
- Usually administered as single high-dose or short course
- For children (per WHO):
- 6–11 months: 100,000 IU once
- 12–59 months: 200,000 IU once every 4–6 months
- Dosage should always follow clinical guidelines or physician direction
📦 PACKING
- Common sizes: 10 mL, 15 mL, or 30 mL bottles
- Comes with dropper or measuring cap
🧊 STORAGE
- Store in a cool, dark place
- Keep tightly closed
- Refrigeration may be required depending on the formulation
💉 Vitamin A Injection – 50,000 IU/mL
✅ DESCRIPTION
A sterile oil-based injectable formulation of Vitamin A used for emergency treatment of deficiency, often where oral route is not possible.
⚖️ COMPOSITION
- Each mL contains 50,000 IU of Vitamin A Palmitate or Acetate
- In oil vehicle (commonly refined peanut or sesame oil)
- May include preservatives like benzyl alcohol
📌 USES
- Severe Vitamin A deficiency with malabsorption or inability to take oral supplements
- Measles with complications
- Emergency supplementation in hospital/nutritional rehabilitation settings
🌟 ADVANTAGES
- Immediate bioavailability
- Effective for patients who are vomiting, unconscious, or have severe gastrointestinal issues
⚠️ PRECAUTIONS
- Intramuscular (IM) only — do not inject intravenously
- Avoid in patients with allergy to oil base or preservatives
- Not recommended for routine use due to toxicity risk
❌ SIDE EFFECTS
- Local pain/swelling at injection site
- Headache, dizziness
- Skin peeling or liver toxicity (if overdosed)
💊 DOSAGE (under strict medical supervision)
- Adults/children: As per WHO or national guidelines
- IM administration only, typically in gluteal muscle
📦 PACKING
- 1 mL ampoules or vials
- Single-dose or multi-dose formats
🧊 STORAGE
- Store below 25°C
- Protect from light and freezing
- Shake well if instructed