Tiotropium Inhalation (DPI) 18 mcg/dose

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💨 Tiotropium Inhalation (DPI) 18 mcg/dose


DESCRIPTION

Tiotropium is a long-acting muscarinic antagonist (LAMA) used as a maintenance bronchodilator in the treatment of chronic obstructive pulmonary disease (COPD) and sometimes in severe asthma. It relaxes airway muscles by blocking acetylcholine at muscarinic receptors.


🧪 FORMULATION

  • Strength: 18 micrograms per capsule/dose
  • Form: Dry Powder Inhaler (DPI), typically administered via a device like HandiHaler® (generic DPI device)
  • Route: Inhalation
  • Dosage: One capsule once daily (contents inhaled via DPI device)

🌿 NATURE

  • Anticholinergic bronchodilator
  • Once-daily maintenance therapy
  • Not a rescue medication

📌 USES

  • Chronic Obstructive Pulmonary Disease (COPD)
    • Chronic bronchitis
    • Emphysema
  • Add-on therapy in some cases of severe asthma

🌟 ADVANTAGES

  • Long-acting — 24-hour effect
  • Reduces COPD exacerbations
  • Improves lung function and exercise tolerance
  • Fewer systemic side effects than oral bronchodilators

⚠️ PRECAUTIONS

  • Do not swallow the capsule — inhale only using device
  • Avoid exposure to eyes (may cause blurred vision, pupil dilation)
  • Caution in:
    • Narrow-angle glaucoma
    • Urinary retention
    • Benign prostatic hyperplasia (BPH)

CONTRAINDICATIONS

  • Hypersensitivity to tiotropium or milk protein (if present)
  • Not for acute asthma attacks or emergency use

💢 SIDE EFFECTS

  • Dry mouth (most common)
  • Sore throat, cough
  • Constipation
  • Headache
  • Dizziness
  • Rare: Urinary retention, glaucoma symptoms

📥 PACKING

  • Commonly packed as capsules in blister strips, with a reusable DPI device

🧊 STORAGE

  • Store at room temperature below 25–30°C
  • Keep capsules in original packaging (protect from moisture)
  • Open blister only immediately before use
  • Keep out of reach of children

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