Here is a detailed overview of Timolol Eye Drops 0.25%:
✅ DESCRIPTION
Timolol Maleate 0.25% Ophthalmic Solution is a non-selective beta-adrenergic blocker used to reduce intraocular pressure (IOP) in patients with glaucoma or ocular hypertension. It works by decreasing the production of aqueous humor in the eye.
🧪 FORMULATION
- Active Ingredient: Timolol Maleate 0.25% (2.5 mg/mL)
- Preservative: Benzalkonium chloride (0.005%)
- Other Excipients:
- Sodium phosphate (buffer)
- Sodium chloride
- Hydrochloric acid / Sodium hydroxide (for pH adjustment)
- Purified water
- Form: Sterile ophthalmic solution (eye drops)
🌿 NATURE
- Type: Non-selective beta-adrenergic receptor blocker
- Pharmacological Class: Antiglaucoma agent (beta-blocker)
- Mechanism of Action:
Blocks beta-receptors in the ciliary body → reduces aqueous humor formation → lowers intraocular pressure
💊 USES
- Primary Uses:
- Open-angle glaucoma
- Ocular hypertension
- Adjunct Therapy:
- Used in combination with other IOP-lowering agents (e.g., prostaglandins, carbonic anhydrase inhibitors)
🌟 ADVANTAGES
- Proven efficacy in reducing IOP
- Rapid onset of action (within 30 minutes)
- Long duration (up to 24 hours) – suitable for once- or twice-daily dosing
- Less ocular irritation compared to some other agents
- Well-tolerated when used as directed
⚠️ PRECAUTIONS
- Ocular Side Effects:
- Burning or stinging on instillation
- Dry eyes
- Blurred vision
- Eye redness
- Systemic Side Effects (due to beta-blocking action):
- Bradycardia (slow heart rate)
- Hypotension (low BP)
- Fatigue
- Breathing difficulty (especially in asthma or COPD patients)
- Depression or mood changes (rare)
- Use with caution in:
- Asthma or chronic obstructive pulmonary disease (COPD)
- Heart block, bradycardia, or heart failure
- Diabetes (can mask hypoglycemia symptoms)
- Thyroid disorders (can mask hyperthyroidism)
- Contact Lens Users:
Remove lenses before use and wait 15 minutes before reinserting.
🧊 STORAGE
- Store at 15°C to 25°C (room temperature)
- Protect from light and moisture
- Keep the bottle tightly closed
- Do not touch the dropper tip to any surface or the eye
- Discard 28 days after opening
- Keep out of reach of children