🔹 Teneligliptin Tablet 20 mg – As Licensed
📄 **Description:
Teneligliptin** is an oral anti-diabetic drug belonging to the DPP-4 inhibitor class. It is used for the management of Type 2 Diabetes Mellitus by improving postprandial and fasting blood glucose levels without causing significant hypoglycemia.
💊 Prescription / Use:
- Indications:
- Type 2 Diabetes Mellitus
- Used as monotherapy or in combination with:
- Metformin
- Sulfonylureas
- Thiazolidinediones
- Insulin
- Dosage:
- Typically 20 mg once daily, with or without food
- Can be increased to 40 mg/day (off-label or in some guidelines) in select cases under supervision
- Route: Oral
- Administration: Swallowed whole with water
🔬 Nature:
- Class: Dipeptidyl Peptidase-4 (DPP-4) Inhibitor (Gliptin)
- Mechanism of Action:
- Inhibits DPP-4 enzyme, prolonging the action of incretin hormones (GLP-1, GIP)
- Enhances insulin secretion in a glucose-dependent manner
- Suppresses glucagon release, reducing hepatic glucose production
- Form: Film-coated tablet
- Color/Appearance: White to off-white tablet, marked with strength or brand label
🌟 Advantages:
- Low risk of hypoglycemia
- Weight-neutral
- Can be used in elderly and renal-impaired patients (with caution)
- Suitable for once-daily dosing
- Improves both fasting and post-meal glucose levels
- Often well-tolerated
📦 Common Packaging:
- Strip packs of 10 tablets (10 x 1)
- Some brands supply in blister cards
- Label includes brand name, generic name, strength, batch, expiry, etc.
🧊 Storage:
- Store at below 30°C in a dry place
- Keep away from moisture, direct sunlight, and children
- Do not use if tablet color changes or after expiry
⚠️ Precautions:
- Use cautiously in:
- Patients with renal insufficiency (dose adjustment may be needed)
- Hepatic impairment
- Heart failure
- Not recommended for Type 1 diabetes or diabetic ketoacidosis
- Monitor for signs of:
- Pancreatitis
- Hypersensitivity reactions
- Joint pain (rare)
👩⚕️ Patient Advice:
- Take at the same time each day
- Can be taken with or without food
- Maintain regular blood sugar monitoring
- Continue prescribed diet and exercise
- Inform doctor of any:
- Stomach pain
- Vomiting
- Severe fatigue
- Allergic reactions
- Not a substitute for insulin in insulin-dependent diabetes