Here is a complete overview of Tenecteplase Injection 30 mg/vial with icons:
💉 Tenecteplase Injection 30 mg/vial
🧪 Nature / Drug Class
🔹 Thrombolytic Agent
🔹 Recombinant tissue plasminogen activator (rtPA)
🔹 Fibrin-specific clot dissolver
🩺 Purpose / Indications
✅ Used for:
- ❤️ Acute ST-Elevation Myocardial Infarction (STEMI) – to dissolve clots and restore coronary blood flow
- 🧠 (Off-label use) in acute ischemic stroke (selected cases under protocol)
- 🫀 Massive pulmonary embolism (in life-threatening settings)
⚙️ Advantages
✔️ Single bolus injection – rapid administration (vs. infusion with alteplase)
✔️ Faster reperfusion in STEMI
✔️ High fibrin specificity – less systemic fibrinolysis
✔️ Lower risk of non-cerebral bleeding compared to older thrombolytics
📦 Common Packaging
📦 Vial with 30 mg lyophilized powder
💧 Comes with sterile water for reconstitution
💉 For intravenous bolus use only
🧪 Also available in 6 mg, 30 mg, 40 mg, and 50 mg strengths
⚠️ Patient Advice / Precautions
🕒 Must be administered as soon as possible within 6 hours of symptom onset in MI
🩸 Monitor for bleeding complications during and after administration
🧪 Check baseline coagulation, BP, and contraindications before use
📉 Avoid use in uncontrolled hypertension, recent stroke/bleeding, major surgery
🧠 Risk of intracranial hemorrhage – requires close monitoring
🚫 Contraindications (selected)
❌ History of hemorrhagic stroke or intracranial neoplasm
❌ Recent head trauma or GI bleeding
❌ Uncontrolled hypertension
❌ Active internal bleeding
🧊 Storage
🌡️ Store powder below 25°C (do not freeze)
💧 Reconstituted solution should be used immediately or within 8 hours if refrigerated
🧒 Keep out of reach of children