Here is the full overview for:
💊 Stavudine + Lamivudine Tablet
Each tablet contains:
- Stavudine (A) – 30 mg
- Lamivudine (B) – 150 mg
🧪 Nature / Drug Class
🔹 Fixed-Dose Combination (FDC) Antiretroviral
🔹 Both are Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
🩺 Purpose / Indications
✅ Treatment of HIV-1 infection in adults and adolescents
✅ Used in combination ART as part of triple therapy
✅ Designed to suppress viral replication and improve immunity
✅ Mostly phased out in many regions due to safer alternatives, but still used where relevant
⚙️ Advantages
✔️ Combines two key NRTIs into one tablet
✔️ Simplifies treatment regimen
✔️ May be used in weight-based dosing protocols
✔️ Cost-effective in certain health programs
📦 Common Packaging
📦 Blister or HDPE bottle packaging
🕒 Usually taken twice daily, based on clinical guidance
💊 Oral solid tablet form
⚠️ Patient Advice / Precautions
🧪 Regular monitoring for:
- Peripheral neuropathy (common with Stavudine)
- Lactic acidosis and hepatomegaly with long-term use
- Hematologic effects (Lamivudine side)
🩸 Report symptoms like tingling, numbness, fatigue, or pain
⏰ Maintain strict daily dosing schedule to prevent resistance
❌ Do not stop medication suddenly
🚫 Contraindications / Cautions
❌ Hypersensitivity to any component
⚠️ Use with caution in:
- Liver disease
- History of neuropathy or pancreatitis
- Pregnancy, especially due to Stavudine-associated risks
🧊 Storage
🌡️ Store at room temperature below 25°C
💊 Keep tablets dry and tightly closed
🔐 Keep away from children