Here is the full overview for:
💊 Stavudine + Lamivudine Dispersible Tablet
Each dispersible tablet contains:
- Stavudine (A) – 6 mg
- Lamivudine (B) – 30 mg
- (p) – indicates pediatric formulation
🧪 Nature / Drug Class
🔹 Fixed-Dose Combination (FDC) Antiretroviral
🔹 Drug classes:
- Stavudine – NRTI (Nucleoside Reverse Transcriptase Inhibitor)
- Lamivudine – NRTI (Nucleoside Reverse Transcriptase Inhibitor)
🩺 Purpose / Indications
✅ Used in pediatric HIV treatment
✅ Helps suppress viral replication
✅ Improves immune function and slows disease progression
✅ Used under weight-band dosing regimens in children
⚙️ Advantages
✔️ Dispersible – easy to administer for infants/small children
✔️ Fixed combination – fewer tablets, better compliance
✔️ Cost-effective option in resource-limited settings
✔️ May be used in national pediatric ART programs
📦 Common Packaging
📦 Blister packs or bottles
💧 Dispersible tablets to be dissolved in clean water before use
📏 Dosing typically based on child’s weight
⚠️ Patient Advice / Precautions
🧪 Monitor for:
- Peripheral neuropathy (Stavudine side effect)
- Lactic acidosis with long-term use
- Hematologic toxicity (Lamivudine-related)
🕒 Ensure adherence to prevent resistance
💊 Do not crush – dissolve completely before administration
🩺 Regular medical follow-up is important
🚫 Contraindications / Cautions
❌ Allergy to Stavudine or Lamivudine
⚠️ Avoid in children with liver dysfunction or pancreatitis
⚠️ Monitor closely if used with other ART drugs that increase neuropathy risk
🧊 Storage
🌡️ Store below 25°C
🚫 Protect from moisture and sunlight
🔐 Keep out of reach of children