✅ Generic Name:
Spironolactone 25 mg Tablet
📄 Description:
Spironolactone is a potassium-sparing diuretic and aldosterone antagonist. It works by blocking the action of aldosterone in the kidneys, promoting sodium and water excretion, while retaining potassium.
Each tablet contains 25 mg of spironolactone, often used for hypertension, heart failure, and conditions related to fluid overload or aldosterone excess.
🌿 Nature / Drug Class:
- Class:
- Aldosterone antagonist
- Potassium-sparing diuretic
- Mechanism of Action:
- Inhibits aldosterone in the distal nephron → promotes Na⁺ excretion and K⁺ retention
- Mild diuretic effect compared to loop diuretics
🎯 Purpose / Indications:
- Heart failure (esp. NYHA Class III–IV)
- Hypertension, especially with hypokalemia
- Liver cirrhosis with ascites
- Nephrotic syndrome
- Primary hyperaldosteronism (Conn’s syndrome)
- Hirsutism and polycystic ovary syndrome (PCOS) (off-label use)
- Hypokalemia prevention (from other diuretics)
✅ Advantages:
- Prevents potassium loss (unlike loop/thiazide diuretics)
- Beneficial in resistant hypertension
- Reduces morbidity and mortality in heart failure
- Used in hormone-related disorders (e.g. hirsutism)
- Oral tablet form allows easy outpatient use
💊 Dosage & Administration:
- Usual adult dose: 25–100 mg/day, depending on condition
- For heart failure: start with 25 mg once daily
- Can be increased cautiously if needed
- Always monitor serum potassium and renal function
📦 Common Packaging:
- Blister packs or strip packs
- Usually: 10 tablets per strip, in boxes of 30 or 100 tablets
- Label: “Spironolactone 25 mg Tablets”
❄️ Storage Conditions:
- Store at 15–30°C (59–86°F)
- Keep in a dry place, away from sunlight
- Protect from moisture and children
👨⚕️ Patient Advice / Precautions:
- Take with food to reduce stomach upset
- Do not take potassium supplements or salt substitutes without doctor’s approval
- Regular blood tests for potassium and kidney function are necessary
- Report signs of high potassium (muscle weakness, irregular heartbeat)
- Avoid NSAIDs, which can worsen kidney function