Mechanism of Action: Increases gamma-aminobutyric acid (GABA) levels in the brain, which has an inhibitory effect on neurotransmission — helping to control seizures and mood swings.
3. Advantages
Broad-spectrum antiepileptic — effective for multiple seizure types
Also used in psychiatry for mood stabilization
Can be used alone or in combination with other antiepileptic drugs
Available in multiple oral forms (tablet, syrup, controlled-release, etc.)
4. Common Packaging
Blister packs or bottle packaging
Usually available in strips of 10 or 15 tablets
May be labeled as:
Sodium Valproate 200 mg
Or Valproic Acid equivalent 200 mg (depending on the brand/formulation)
5. Storage Conditions
Temperature: Store below 25°C
Moisture: Protect from moisture; keep in original packaging
Light: Keep away from direct sunlight
6. Patient Advice
Take the tablet with food to minimize gastrointestinal side effects.
Do not crush or chew (unless it’s a chewable or dispersible form).
Take regularly at the same time daily for best effect.
Do not stop the medicine suddenly without medical advice — risk of seizure recurrence.
Avoid alcohol while on valproate.
Women of childbearing age: Valproate can cause serious birth defects — use effective contraception and consult your doctor before planning pregnancy.
Inform your doctor if you experience:
Unusual tiredness, vomiting, jaundice (yellowing of eyes/skin)
