Sodium Valproate Injection 100 mg/mL - Life Care Drugs and Medicines

Generic Name: Sodium Valproate
Formulation: Injection (Solution for IV use)
Strength: 100 mg/mL
Route of Administration: Intravenous (IV)
Prescription Required: ✔️ Yes
Indications:
- Emergency treatment of status epilepticus (prolonged or repeated seizures)
- When oral administration is not possible in epilepsy or bipolar disorder
- Short-term use during perioperative periods or hospitalization

Drug Class: Anticonvulsant / Antiepileptic
Mechanism of Action:
- Increases GABA levels in the brain (inhibitory neurotransmitter)
- Stabilizes neurons by modulating sodium and calcium channels
- Suppresses abnormal electrical activity in the brain

Rapid action in emergency situations (e.g., seizures, unconscious patient)
Useful in patients unable to take oral medications
Can be used for loading dose followed by oral maintenance
Lower risk of cardiopulmonary side effects compared to phenytoin or phenobarbital

Concentration: 100 mg/mL
Vial Size: Usually 3 mL, 5 mL, or 10 mL glass vials
Total Content per Vial: 300 mg, 500 mg, or 1,000 mg
Packaging Type: Single-use glass ampoule or vial
May be labeled as:
- “Sodium Valproate Injection”
- Or “Valproate Sodium Solution for IV Use”

Store below 25°C
Do not refrigerate or freeze
Protect from light
Use immediately after opening the vial
Dilution before IV infusion: Usually diluted in normal saline or 5% dextrose

This medicine is administered by healthcare professionals only — usually in hospital or emergency settings
Inform medical staff about:
- Allergies, especially to valproate or other antiepileptics
- Liver disease, urea cycle disorders, or clotting problems
Do not self-administer under any circumstance
Watch for side effects after administration, especially:
- Sleepiness, confusion, or mood changes
- Nausea, vomiting, or abdominal pain
- Yellowing of the skin or eyes (jaundice)