Here is the complete clinical profile for:
💉 Ringer Lactate Injection (as per IP)
✅ DESCRIPTION
Ringer Lactate Injection is a sterile, isotonic intravenous solution used for fluid and electrolyte replenishment. It contains a balanced mix of sodium, potassium, calcium, and lactate, closely resembling plasma electrolyte composition.
⚖️ COMPOSITION (as per IP – per 1000 mL)
- Sodium chloride – 6.0 g
- Sodium lactate – 3.1 g
- Potassium chloride – 0.4 g
- Calcium chloride – 0.27 g
- Water for injection – q.s.
- Total ions:
- Sodium (Na⁺): ~130 mEq
- Potassium (K⁺): ~4 mEq
- Calcium (Ca²⁺): ~3 mEq
- Chloride (Cl⁻): ~109 mEq
- Lactate: ~28 mEq
- pH: 6.0–7.5
- Osmolarity: ~273 mOsm/L
🌿 NATURE
- Isotonic, crystalloid fluid
- Contains buffering agent (lactate)
- Used for volume replacement and acid-base balance
📌 USES
- Rehydration in dehydration or burns
- Surgical fluid replacement
- Treatment of acidosis (mild to moderate metabolic)
- Trauma and blood loss (hypovolemia)
- Used in obstetrics, critical care, and emergency settings
🌟 ADVANTAGES
- Electrolyte balance closely matches extracellular fluid
- Lactate is metabolized to bicarbonate, helping correct acidosis
- Suitable for large-volume infusion
⚠️ PRECAUTIONS
- Use with caution in:
- Renal impairment
- Heart failure
- Severe liver dysfunction (impaired lactate metabolism)
- Do not mix with blood transfusions in the same IV line — calcium may cause clotting
❌ CONTRAINDICATIONS
- Hyperkalemia, hypercalcemia
- Severe alkalosis
- Anuria or severe renal impairment
- Lactic acidosis
💢 SIDE EFFECTS
- Fluid overload (edema, pulmonary congestion)
- Electrolyte imbalance
- Local irritation or infection at the injection site
- Hyperkalemia or hypercalcemia if overdosed
📦 PACKING
- Available in plastic infusion bottles or flexible pouches
- Common sizes: 500 mL, 1000 mL
🧊 STORAGE
- Store at below 30°C
- Protect from excessive heat and freezing
- Use immediately after opening
- Do not use if solution is cloudy or has particulates