Here is the complete pharmaceutical profile for:
💊 Pyridoxine Tablet 100 mg
(Vitamin B6)
✅ DESCRIPTION
Pyridoxine (Vitamin B6) is a water-soluble vitamin essential for metabolism of amino acids, production of neurotransmitters (e.g. serotonin, dopamine, GABA), and maintenance of nervous system and immune health. The 100 mg dose is a high-strength therapeutic formulation, often used in specific clinical settings like neuropathy and drug-induced deficiency.
⚖️ COMPOSITION
- Each tablet contains:
- Pyridoxine Hydrochloride … 100 mg
- Excipients … q.s.
🧪 NATURE
- Solid oral dosage form
- May be white, round, or scored tablets for easy splitting
- Odorless or slightly characteristic odor
📌 USES
- Treatment of severe pyridoxine deficiency
- Peripheral neuropathy, especially:
- Drug-induced (e.g. isoniazid, hydralazine, penicillamine)
- Diabetic/alcoholic neuropathy
- PMS and morning sickness (as combination therapy)
- Homocystinuria, xanthurenic aciduria, and other rare metabolic disorders
- As adjunct in seizure disorders and anemia management
🌟 ADVANTAGES
- High dose for targeted therapeutic effect
- Supports neuroprotection
- Often prescribed with isoniazid therapy in tuberculosis patients
- Can reduce symptoms of fatigue, irritability, and nerve dysfunction
⚠️ PRECAUTIONS
- Long-term high-dose use (>200 mg/day) may cause sensory neuropathy
- Use with caution in:
- Renal or hepatic impairment
- Patients on levodopa alone (interferes with its efficacy)
❌ CONTRAINDICATIONS
- Hypersensitivity to pyridoxine
- Should not be used as sole treatment for seizure disorders or psychiatric conditions without medical supervision
💢 SIDE EFFECTS
- Rare at standard doses, but high-dose (≥100 mg/day long-term) may cause:
- Numbness or tingling in hands/feet
- Ataxia
- Fatigue or headache
- Nausea
💊 DOSAGE & ADMINISTRATION
- Typical adult dose:
- 100 mg once or twice daily, depending on indication
- Best taken after meals
- Duration based on clinical condition and doctor’s advice
📦 PACKING
- Available in strips of 10, 15, or 30 tablets
- HDPE bottles for hospital supply
- Each pack labeled with dose, batch number, expiry date
🧊 STORAGE
- Store at room temperature (<25°C)
- Protect from light and moisture
- Keep out of reach of children