Here’s a detailed overview of Pyrazinamide Oral Liquid 250 mg/5 mL (p) with key sections and icon-style formatting:
💧 Pyrazinamide Oral Liquid 250 mg/5 mL (p)
🧪 Nature / Drug Class:
- First-line antitubercular agent
- Pediatric formulation for children with TB who cannot swallow tablets
✅ Description / Purpose:
- Treats active tuberculosis in children
- Kills Mycobacterium tuberculosis inside infected cells
- Allows accurate weight-based dosing
⚖️ Dosage:
- Children: 30–40 mg/kg once daily, measured using a calibrated oral syringe or measuring cup
- Adults: Usually tablet form is preferred
Note: Exact dosage and duration must follow a doctor or TB specialist prescription
💡 Advantages:
- Easy for children or patients unable to swallow tablets
- Provides flexible, weight-based dosing
- Effective in combination therapy to prevent drug resistance
⚠️ Prescription / Precautions:
- ❌ Avoid alcohol (liver toxicity risk)
- ⚠️ Monitor liver function
- ⚠️ Monitor uric acid levels (risk of gout)
- ⚠️ Can cause gastrointestinal upset (nausea, vomiting)
- ✅ Complete full prescribed course
🩺 Common Side Effects:
- Nausea, vomiting, diarrhea
- Abdominal pain
- Rare: hepatotoxicity, rash, joint pain
📦 Common Packaging:
- Oral liquid: 250 mg per 5 mL
- Usually in bottles of 30–100 mL
🛡️ Storage Guidelines:
- 🌡 Store in cool, dry place (<30°C)
- ☀️ Protect from direct sunlight and moisture
- 🚫 Keep out of reach of children
- 💊 Keep bottle tightly closed
- 🔄 Shake well before each use