Here is the detailed overview for:
💊 Procarbazine Capsule 50 mg
🧪 Nature / Drug Class
🔹 Alkylating-like antineoplastic agent
🔹 Belongs to the methylhydrazine derivative group
🔹 Cytotoxic chemotherapy drug
🩺 Purpose / Indications
✅ Used in treatment of:
- Hodgkin’s lymphoma (part of MOPP regimen)
- Certain brain tumors (e.g., glioblastoma multiforme, astrocytoma)
- Occasionally used in combination with other agents for non-Hodgkin lymphoma
⚙️ Advantages
✔️ Effective oral chemotherapy option
✔️ Useful in combination therapy for resistant malignancies
✔️ Crosses the blood-brain barrier, helpful in brain tumors
📦 Common Packaging
📦 Capsule form – usually 50 mg per capsule
💊 Often supplied in bottles or blister packs
📅 Dosing varies – typically in cycles (as part of combination protocol)
⚠️ Patient Advice / Precautions
🥗 Avoid alcohol and tyramine-rich foods (risk of hypertensive crisis)
🚫 No self-medication – taken strictly under oncologist supervision
🩺 Regular monitoring of:
- CBC (blood counts)
- Liver and kidney function
🤒 Report symptoms like sore throat, fever, bleeding, or unusual fatigue
📅 Take at the same time daily, preferably after food to reduce nausea
🚫 Contraindications / Cautions
❌ Hypersensitivity to procarbazine
❌ Pregnancy and breastfeeding
⚠️ Use with caution in:
- Hepatic or renal impairment
- Patients with seizure disorders
- MAOI interactions — avoid certain drugs and foods
🧊 Storage
🌡 Store at room temperature (15–25°C)
☀️ Protect from light and moisture
🔒 Keep out of reach of children