Active Ingredient: Contains 10 mg of phytomenadione, which is the synthetic form of Vitamin K1 (also known as phylloquinone).
Form: It is an oral tablet formulation used to provide a specific dose of this fat-soluble vitamin.
Advantages
Reverses Anticoagulant Effects: Highly effective in reversing the effects of coumarin-derived anticoagulants (like warfarin) in cases of overdose or excessive bleeding, by restoring normal clotting factor levels.
Treats Deficiency: Effectively replenishes low levels of vitamin K in the body, which are essential for proper blood clotting and bone health.
Uses
Anticoagulant-Induced Hypoprothrombinemia: Primarily used to treat bleeding or prevent hemorrhage caused by an overdose of oral anticoagulants.
Vitamin K Deficiency: Indicated for hypoprothrombinemia (a clotting disorder) resulting from vitamin K deficiency due to various causes, such as malabsorption syndromes (e.g., obstructive jaundice, celiac disease, ulcerative colitis) or prolonged antibiotic therapy.
Nature
Fat-Soluble Vitamin: Phytomenadione is a fat-soluble vitamin, meaning its absorption in the intestines requires the presence of bile salts.
Co-factor for Clotting Factors: It acts as a crucial co-factor for the enzyme gamma-glutamyl carboxylase, which is responsible for the activation of specific vitamin K-dependent clotting factors (Factors II, VII, IX, X) and anticoagulant proteins (Protein C and Protein S) in the liver. Without sufficient Vitamin K1, these proteins remain inactive, leading to impaired blood clotting.
Storage
Temperature: Store Phytomenadione Tablets 10 mg at controlled room temperature, typically below 25∘C or between 20∘C to 25∘C.
Protection: Keep the tablets in their original, tightly closed container or blister pack, protected from direct light, heat, and moisture, as vitamin K1 is degraded by light.
