Here is the full overview for:
💉 Pegylated Interferon Alfa-2a Injection 80 mcg
🧪 Nature / Drug Class
🔹 Long-acting interferon
🔹 Biologic immunomodulator
🔹 Pegylated form (PEG) allows sustained release and weekly dosing
🩺 Purpose / Indications
✅ Treatment of chronic hepatitis B and chronic hepatitis C
✅ Also used in some oncologic and hematologic conditions
✅ Acts by modulating immune response and inhibiting viral replication
⚙️ Advantages
✔️ Once-weekly dosing due to pegylation
✔️ Long-acting — better patient adherence
✔️ Can be used in combination with antiviral medications
✔️ Reduces liver inflammation and viral load
📦 Common Packaging
📦 Prefilled syringe or vial
💉 Typically supplied in strengths of 80 mcg, 135 mcg, or 180 mcg
🕒 For subcutaneous injection, administered once weekly
📄 Comes with patient information leaflet and dose instructions
⚠️ Patient Advice / Precautions
🧪 Monitor for:
- Flu-like symptoms (fever, fatigue, muscle aches)
- Mood changes or depression
- Bone marrow suppression (CBC monitoring required)
- Liver function regularly
🚫 Avoid alcohol; it may worsen liver damage
💉 Injection site reactions possible — rotate sites
👩⚕️ Should be used under close medical supervision
🚫 Contraindications / Cautions
❌ Autoimmune hepatitis or severe psychiatric illness
⚠️ Use caution in:
- Cardiac disease
- Seizure disorders
- History of depression or suicidal ideation
❌ Not recommended during pregnancy
🧊 Storage
🧊 Refrigerate at 2°C to 8°C
🚫 Do not freeze
🌞 Protect from direct light
📦 Keep in original packaging until use