💊 Paracetamol Suppository 80 mg
📘 **Description:
Paracetamol Suppository 80 mg** is a rectal dosage form of paracetamol (acetaminophen), used to manage mild to moderate pain and fever in pediatric patients or patients unable to take oral medications. It is typically used in children aged 6 months to 6 years, depending on body weight and medical advice.
🔬 Nature / Mechanism of Action:
- Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer).
- It works by inhibiting prostaglandin synthesis in the central nervous system, reducing pain perception and body temperature.
- Suppository form allows absorption through rectal mucosa, bypassing the gastrointestinal tract.
🩺 Prescription / Uses:
| Indication | Purpose |
|---|---|
| Fever | Lowering body temperature |
| Mild to moderate pain | Headache, teething pain, post-vaccine fever, etc. |
| Patients with nausea/vomiting | When oral administration is not suitable |
| Post-surgery | Pediatric pain relief after minor procedures |
✅ Advantages:
- Ideal for vomiting or unconscious children
- Bypasses gastric irritation
- Fast absorption via rectal mucosa
- Useful during nighttime to avoid waking child for oral medicine
⚠️ Precautions:
- Use correct weight-based dose for children
- Do not exceed maximum daily limit
- Avoid in case of rectal irritation, bleeding, or diarrhea
- Use with caution in liver disease
- Wash hands before and after use; insert carefully with clean gloves or applicator if needed
📏 Typical Pediatric Dosage:
| Weight | Typical Dose (rectal) |
|---|---|
| 6–11 kg | 80 mg (1 suppository), every 6 hours |
| Max daily dose | 60 mg/kg/day (divided into 4–6 doses) |
⚠️ Always follow pediatrician’s or healthcare provider’s instructions. Avoid combining with other paracetamol products.
🚨 Possible Side Effects:
- Mild rectal irritation
- Rare allergic reaction (rash, itching, swelling)
- Overdose risk if combined with other paracetamol-containing medicines
- Liver toxicity in high or repeated doses
💊 Drug Interactions:
- Caution with:
- Other paracetamol formulations
- Hepatotoxic drugs like isoniazid, rifampicin
- Alcohol (in older children/adolescents)
📦 Storage:
- Store in a cool place (below 25°C), preferably refrigerated
- Protect from heat (may melt)
- Keep out of reach of children