Here is a complete drug information summary for Oxytocin Injection 10 IU/mL (no brand names included):
💉 Oxytocin Injection 10 IU/mL
✅ DESCRIPTION
Oxytocin is a synthetic uterotonic hormone used to stimulate uterine contractions during labor and to control postpartum bleeding. It is chemically identical to the natural oxytocin hormone produced by the posterior pituitary.
🧪 FORMULATION
- Active Ingredient: Oxytocin – 10 IU per 1 mL
- Dosage Form: Clear, sterile, aqueous injection
- Route of Administration: Intramuscular (IM) or Intravenous (IV)
- Packaging: 1 mL ampoule or vial (single-dose)
🌿 NATURE
- Type: Synthetic peptide hormone
- Pharmacological Class: Uterotonic / Hormone
- Action: Stimulates oxytocin receptors in uterine smooth muscle → causes rhythmic contractions → aids in labor and postpartum control of bleeding
💊 USES
🔹 Primary Indications:
- Induction or augmentation of labor (under medical supervision)
- Prevention and treatment of postpartum hemorrhage (PPH)
- Facilitation of uterine involution after delivery
- Post-abortion evacuation
🌟 ADVANTAGES
- Potent and rapid uterotonic action
- Useful in both emergency and scheduled obstetric care
- Short half-life allows careful dosing control
- Essential medicine in maternal care
⚠️ PRECAUTIONS
❗ Contraindications:
- Obstructed labor
- Malpresentation (e.g., transverse lie)
- Previous uterine surgery (e.g., C-section)
- Fetal distress without immediate delivery access
- Hypersensitivity to oxytocin
💢 Side Effects:
- Uterine hyperstimulation → rupture (rare but serious)
- Water intoxication (with prolonged IV infusion)
- Nausea, vomiting
- Bradycardia or arrhythmias (in fetus or mother)
- Hypotension (especially if given as rapid IV bolus)
📅 DOSAGE GUIDE
| Clinical Use | Recommended Dose |
|---|---|
| Labor induction (IV infusion) | Start at 1–2 milliunits/min → increase every 30 min as needed |
| PPH prevention (after delivery) | 10 IU IM or slow IV after delivery of placenta |
| PPH treatment | 10 IU IM or slow IV bolus |
📝 Note: Always monitor uterine tone, fetal heart rate, and maternal vitals during use.
🧊 STORAGE
- Store at 2°C to 8°C (refrigerated)
- Protect from light
- Do not freeze
- Discard after opening (single-use vial or ampoule)
- Maintain cold chain during transportation