💉 Ondansetron Injection 2 mg/mL – As Licensed
📄 Description:
Ondansetron Injection is a selective serotonin 5-HT₃ receptor antagonist used to prevent and treat nausea and vomiting associated with chemotherapy, radiotherapy, surgery, and acute medical conditions. It is administered intravenously (IV) or intramuscularly (IM).
🧾 Prescription / Indications:
Prescribed for:
- Prevention and treatment of chemotherapy-induced nausea and vomiting (CINV)
- Prevention of postoperative nausea and vomiting (PONV)
- Radiotherapy-induced nausea and vomiting (RINV)
Typical Adult Dose (IV/IM):
- 4 to 8 mg IV/IM before induction of anesthesia or chemotherapy
- May be repeated or followed by infusion depending on protocol
Pediatric Dose:
- Dose adjusted based on body weight (e.g., 0.1–0.15 mg/kg), especially in chemotherapy or postoperative settings
🔬 Nature:
- Form: Sterile aqueous solution for injection
- Strength: 2 mg/mL
- Route: Intravenous (IV) or Intramuscular (IM)
- Pharmacologic Class: Antiemetic (5-HT₃ antagonist)
🌟 Advantages:
- Fast-acting via IV or IM route
- Effective in controlling severe or sudden vomiting
- Useful in hospital and emergency settings
- Safe profile with minimal sedation
📦 Packaging:
- Available in ampoules or vials
- Common sizes: 2 mL (4 mg), 4 mL (8 mg)
- Packaged in glass ampoules or plastic vials in sterile blisters
🧊 Storage:
- Store at 15–30°C (59–86°F)
- Protect from light
- Do not freeze
- Discard if solution appears discolored or cloudy
⚠️ Precautions:
- Use with caution in patients with:
- Liver impairment (maximum dose may be reduced)
- Prolonged QT interval or using other QT-prolonging drugs
- Avoid mixing with incompatible IV fluids
- Monitor ECG in high-risk cardiac patients
- Injection site reactions possible (pain, redness)
Common side effects:
- Headache
- Constipation
- Dizziness
- Injection site pain
- Rare: hypersensitivity, arrhythmias
👩⚕️ Patient Advice:
- Administered only by a healthcare professional
- Inform your doctor if you have:
- Heart rhythm disorders
- Liver disease
- Known drug allergies
- Report any chest pain, dizziness, or allergic reactions immediately
- Stay seated/lying down after injection to avoid dizziness