💉 Morphine Injection 10 mg/mL
📘 Description:
Morphine Injection 10 mg/mL is a sterile, preservative-free or preserved solution containing morphine sulfate or morphine hydrochloride intended for parenteral administration. It is an opioid analgesic used for the relief of severe acute and chronic pain.
🔬 Nature / Pharmacological Class:
- Class: Opioid Analgesic (Narcotic)
- Mechanism of Action: Binds to mu-opioid receptors in the CNS, altering pain perception and response
- Onset: 5–10 minutes (IV); 10–30 minutes (IM/subcut)
- Duration: 3–5 hours (short-acting)
🩺 Prescription / Uses:
| Condition | Use |
|---|---|
| Postoperative pain | IM/IV for moderate to severe pain relief |
| Myocardial infarction (MI) | Reduces pain, anxiety, and preload |
| Cancer pain or palliative care | Continuous infusion or intermittent dosing |
| Trauma, burns | Short-term acute pain relief |
| Obstetric analgesia | Low-dose IM/subcut administration (caution) |
✅ Advantages:
- Rapid and effective pain control
- Versatile routes: IV, IM, Subcut
- Can be titrated precisely for individualized response
- Effective in pre-anesthesia and palliative care settings
⚠️ Precautions:
Use cautiously in:
- Respiratory depression or COPD
- Head injuries (may mask signs of elevated ICP)
- Liver/kidney impairment
- Hypotension or shock
- Patients with a history of drug or alcohol dependence
- Elderly, debilitated, or very young patients
📏 Dosage (Adult Typical):
| Route | Dose | Frequency |
|---|---|---|
| IV | 2.5–10 mg | Every 4 hours or as needed |
| IM/Subcut | 5–20 mg | Every 4–6 hours as needed |
Titrate carefully. Start low in opioid-naïve patients.
For IV use, administer slowly over 4–5 minutes.
📦 Storage:
- Store at 25°C (controlled room temperature)
- Protect from light
- Keep away from unauthorized access (Schedule H1 or Narcotic in many countries)