Metronidazole Injection 500 mg/100 mL

📌 Metronidazole Injection 500 mg/100 mL

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💊 Description:

1. Metronidazole Injection is a parenteral antimicrobial solution containing 500 mg of metronidazole in 100 mL.
2. It is a sterile, ready-to-use intravenous infusion, typically supplied in plastic infusion bags or bottles.
3. The solution is clear to pale yellow, with a slightly bitter odor.
4. It is free of preservatives and designed for direct intravenous administration.
5. Each mL contains 5 mg of metronidazole, dissolved in isotonic solution with pH adjusted.

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🌿 Nature:

1. It is a nitroimidazole derivative with potent antiprotozoal and anaerobic antibacterial properties.
2. Exhibits bactericidal activity by damaging microbial DNA and inhibiting nucleic acid synthesis.
3. The IV formulation ensures rapid onset of action, ideal for severe infections.
4. Shows high bioavailability, almost equivalent to oral administration.
5. Especially useful in patients who cannot take oral medications.

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✅ Advantages:

1. Provides immediate and reliable plasma levels for critically ill patients.
2. Effective against anaerobic infections in various body compartments (brain, abdomen, pelvis).
3. Useful for perioperative prophylaxis in colorectal and gynecological surgeries.
4. Can be combined with other antibiotics like cephalosporins for broader coverage.
5. Reduces microbial burden in hospital-acquired infections and sepsis.

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🩺 Uses:

1. Treatment of serious anaerobic infections, including intra-abdominal and pelvic infections.
2. Used in septicemia, osteomyelitis, and brain abscesses caused by anaerobic bacteria.
3. Prevention of post-operative infections in abdominal and gynecological surgeries.
4. Management of Clostridium difficile colitis when oral therapy is not possible.
5. Supportive treatment in mixed aerobic/anaerobic infections alongside other agents.

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❄️ Storage:

1. Store below 25°C (77°F); do not freeze the injection.
2. Keep in the original packaging to protect from light.
3. Discard if the solution appears cloudy, discolored, or contains particulate matter.
4. Once opened, use immediately or within recommended time frames (usually 24 hours).
5. Keep away from children and do not reuse any portion of the leftover solution.

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