Here is a clear and complete overview of:
💉 Meropenem Powder for Injection 500 mg (as trihydrate)
🌿 Nature / Drug Class:
- Meropenem is a broad-spectrum beta-lactam antibiotic
- Belongs to the Carbapenem class
- Bactericidal – kills bacteria by disrupting cell wall synthesis
🎯 Purpose / Indications:
Used to treat moderate to severe bacterial infections, including:
- Pneumonia (community- and hospital-acquired)
- Urinary tract infections (UTI)
- Intra-abdominal infections
- Skin and soft tissue infections
- Meningitis
- Sepsis and febrile neutropenia
- Effective against multi-drug resistant (MDR) organisms
✅ Advantages:
- Broad-spectrum – works against many gram-positive, gram-negative, and anaerobic bacteria
- Often used when other antibiotics fail
- Can be used in ICU, emergency, and critical care settings
- Rapid action when given intravenously (IV)
💉 Form & Administration:
- Supplied as a powder for injection (500 mg Meropenem as trihydrate)
- Must be reconstituted with sterile water or suitable IV fluid before use
- Given via IV injection or infusion, usually over 15–30 minutes
- Dosage and frequency depend on infection severity, kidney function, and patient weight
⚠️ Patient Advice / Precautions:
- Should be used only under medical supervision in hospital settings
- Adjust dose in renal (kidney) impairment
- Watch for allergic reactions, especially in patients allergic to penicillin or other beta-lactam antibiotics
- Possible side effects:
- Diarrhea
- Nausea or vomiting
- Headache
- Rash or infusion-site reactions
- Rare: Seizures, especially in high doses or patients with kidney problems
📦 Common Packaging:
- Glass vial containing 500 mg Meropenem (as trihydrate)
- Supplied with or without a separate diluent
🧊 Storage:
- Store vials at room temperature (below 25°C), away from light
- Once reconstituted, use within specified time frame (usually within 1–2 hours or refrigerated up to 12–24 hours depending on guidelines)
- Do not freeze reconstituted solution