🔹 Medroxyprogesterone Acetate Tablet 10 mg – As Licensed
📄 Description:
Medroxyprogesterone Acetate (MPA) 10 mg is a synthetic progestin used to treat various hormonal and gynecological conditions, including menstrual disorders, abnormal uterine bleeding, and endometrial hyperplasia. It works similarly to the natural hormone progesterone.
💊 Prescription / Use:
Indications:
- Secondary amenorrhea (absence of menstruation)
- Abnormal uterine bleeding due to hormonal imbalance
- Prevention of endometrial hyperplasia in postmenopausal women on estrogen therapy
- Hormone replacement therapy (HRT)
- Can be part of fertility treatments
Typical Dosage:
- 5–10 mg once daily for 5 to 10 days, usually during the second half of the menstrual cycle (e.g., day 16 to 25)
- Prescribed dose may vary by indication and individual response
Route: Oral (by mouth)
🔬 Nature:
- Type: Synthetic progestin hormone
- Class: Hormonal therapy
- Mechanism of Action:
- Stabilizes the endometrial lining
- Mimics natural progesterone
- Suppresses pituitary gonadotropin secretion
🌟 Advantages:
- Regulates menstrual cycles
- Treats abnormal bleeding
- Prevents endometrial overgrowth in women taking estrogen
- Non-invasive alternative to surgery in some menstrual disorders
- Well-tolerated and effective in short-course therapy
📦 Packaging:
- Supplied in blister packs of 10, 30, or 100 tablets
- Tablet is usually white or off-white
- Label includes:
- Drug name and strength
- Manufacturer details
- Batch no. and expiry date
🧊 Storage:
- Store below 25°C in a cool, dry place
- Protect from light and moisture
- Keep out of reach of children
⚠️ Precautions:
- Contraindications:
- Pregnancy (unless specifically indicated)
- Undiagnosed vaginal bleeding
- Active or history of thrombosis, stroke, or liver disease
- Known/suspected breast or genital cancers
- Use with caution in:
- Diabetics
- Women with a history of mood disorders
- Patients prone to fluid retention, seizures, or asthma
Possible Side Effects:
- Headache, dizziness
- Breast tenderness
- Nausea or bloating
- Irregular menstrual bleeding
- Mood swings, fatigue
- Weight gain (water retention)
👩⚕️ Patient Advice:
- Take at the same time daily
- Follow your doctor’s instructions on timing in your cycle
- If a dose is missed, take it as soon as remembered unless it’s nearly time for the next dose
- Not a contraceptive at this dose — use separate birth control if required
- Inform your doctor if you experience:
- Vision changes
- Leg pain/swelling
- Severe headache or mood changes
- Regular follow-up may be required during long-term use