Premedication before surgery or medical procedures (oral sedation)
Adjunct treatment of acute seizures (if IV form is not available or suitable)
Short-term relief of agitation or acute stress
📄 2. Description:
Active Ingredient: Lorazepam 2 mg
Dosage Form: Oral tablet
Appearance: Typically white, round or oval tablets; may be scored for splitting
Route of Administration: Oral
🔬 3. Nature / Drug Class:
Pharmacological Class: Benzodiazepine
Mechanism: Enhances GABA (gamma-aminobutyric acid) activity at the GABA-A receptor, resulting in anxiolytic, sedative, muscle relaxant, and anticonvulsant effects
🌟 4. Advantages:
Rapid onset (30–60 minutes)
Effective for short-term management of anxiety, agitation, and sleep disturbances
More potent than the 1 mg dose for stronger sedation or severe symptoms
Less accumulation compared to diazepam (shorter half-life)
📦 5. Common Packaging:
Strength
Form
Packaging
2 mg
Oral tablet
Blister packs (10 or 15 per strip), bottles (30s, 100s)
🧊 6. Storage:
Store at 15–30°C (59–86°F)
Protect from light, heat, and moisture
Keep in original container
Keep out of reach of children
👩⚕️ 7. Patient Advice:
Take exactly as prescribed; do not increase the dose on your own
May cause drowsiness, dizziness, or impaired coordination — avoid driving or using machinery
Avoid alcohol and other CNS depressants
Do not stop suddenly after regular use — risk of withdrawal symptoms
May be habit-forming with prolonged or unsupervised use
Inform your doctor if you’re pregnant, breastfeeding, or have liver disease, depression, or substance use history
🎯 8. Purpose / Clinical Use:
Condition
Role of Lorazepam 2 mg
Generalized Anxiety
Short-term symptom control
Panic attacks
Acute relief
Severe insomnia
Short-term use for sleep initiation
Preoperative sedation
Calming before surgery or procedures
Status epilepticus (oral)
Adjunct if IV not feasible
Acute agitation
Sedation in psychiatric or emergency settings
⚠️ 9. Warnings / Precautions:
Not suitable for long-term therapy without supervision
Use lower doses in elderly or debilitated patients
Monitor for paradoxical reactions (restlessness, aggression)