Adjunctive therapy in acute seizures or status epilepticus (oral use less preferred in emergencies)
📄 2. Description:
Active Ingredient: Lorazepam 1 mg
Form: Oral tablet
Color/Shape: Usually white, round or oval, often scored
Route: Oral
🔬 3. Nature / Class:
Therapeutic Class: Benzodiazepine
Mechanism of Action: Enhances the effect of GABA (an inhibitory neurotransmitter) by binding to GABA-A receptors → produces calming, anxiolytic, sedative, and muscle relaxant effects.
🌟 4. Advantages:
Rapid onset of action (within 30–60 minutes)
Short half-life compared to diazepam → reduced accumulation
Effective for short-term anxiety control
Can be used in both hospital and outpatient settings
📦 5. Common Packaging:
Strength
Form
Packaging
1 mg
Oral tablet
Blister packs (10s/strip), bottle (100s)
🧊 6. Storage:
Store at 15–30°C (59–86°F)
Protect from light and moisture
Keep out of reach of children
Store in original packaging
👩⚕️ 7. Patient Advice:
Do not drive or operate machinery after taking lorazepam — may cause drowsiness or impaired coordination
Avoid alcohol while using this medication
Take only as prescribed — risk of dependence or withdrawal with prolonged use
Do not stop abruptly if taken for more than a few weeks — tapering may be necessary
Report any unusual mood changes, confusion, or trouble breathing
🎯 8. Purpose / Uses:
Condition
Use
Anxiety disorders
First-line short-term treatment
Insomnia (due to anxiety)
Sleep initiation aid
Pre-surgical sedation
Calms nerves before procedures
Seizure adjunct (chronic)
As part of maintenance care
⚠️ 9. Precautions / Warnings:
Not for long-term use — risk of addiction
Use with caution in elderly — may increase fall risk
Adjust dose in hepatic impairment
Avoid during pregnancy and breastfeeding unless essential
May cause paradoxical reactions (e.g., agitation) in some patients
Increased effects when used with opioids or CNS depressants
