💊 Levetiracetam Oral Liquid 100 mg/mL (p)
📌 1. Prescription / Indication:
Levetiracetam oral solution is prescribed for the treatment of epilepsy, specifically for:
- Partial-onset seizures
- Myoclonic seizures (in juvenile myoclonic epilepsy)
- Generalized tonic-clonic seizures
✅ Approved for adults and children ≥1 month (dose adjusted by weight and age)
📄 2. Description:
- Form: Oral liquid / solution
- Strength: 100 mg of Levetiracetam per 1 mL
- Route: Oral
- Color: Clear to yellowish solution (may vary slightly)
- Bottle size: Commonly 100 mL or 300 mL bottles with dosing syringe
🔬 3. Nature / Class:
- Class: Antiepileptic / Anticonvulsant
- Mechanism of Action:
Binds to SV2A (synaptic vesicle protein), modulating neurotransmitter release and stabilizing neuronal activity.
🌟 4. Advantages:
- Easier administration for:
- Pediatric or elderly patients
- Patients with difficulty swallowing tablets
- Precise dose titration possible
- Useful when fine dose adjustment is needed
- Rapid absorption with predictable effect
- Can be used as monotherapy or add-on therapy
📦 5. Common Packaging:
| Container | Volume | Extras |
|---|---|---|
| Amber PET Bottle | 100–300 mL | Dosing syringe or measuring cup |
| Tamper-evident cap | Included | Child-resistant in many cases |
🧊 6. Storage:
- Store at 15°C–30°C (59°F–86°F)
- Keep bottle tightly closed
- Do not freeze
- Store away from light and moisture
- Use within a specific number of days after opening (check label)
👩⚕️ 7. Patient Advice:
- Use the measuring syringe or spoon provided
- Shake gently before use (if instructed)
- Take at consistent times daily, with or without food
- Do not mix with other medicines or liquids unless advised
- Watch for:
- Drowsiness, dizziness, or mood changes
- Aggression, irritability, or depression—report to doctor
- Do not stop abruptly without doctor advice
- Missed dose? Take ASAP unless near next dose
- Safe in children but needs weight-based dosing
🎯 8. Purpose / Uses:
| Condition | Role |
|---|---|
| Partial seizures | Monotherapy or adjunct |
| Myoclonic seizures | Add-on (juvenile myoclonic epilepsy) |
| Generalized tonic-clonic seizures | Add-on therapy |
⚠️ 9. Precautions / Warnings:
- Adjust dose in renal impairment
- Caution in patients with behavioral disorders
- Monitor for suicidal ideation, especially in adolescents
- Limited use in pregnancy—doctor’s risk-benefit judgment needed
- Do not use after expiry date or if solution becomes cloudy or discolored