Here is the complete information for Leuprolide Acetate in your required format:
💉 Leuprolide Acetate
🧾 Description:
Leuprolide acetate is a synthetic analog of gonadotropin-releasing hormone (GnRH or LHRH). It works by initially stimulating and then significantly reducing the production of sex hormones (testosterone in males, estrogen in females) when used continuously.
🔬 Nature / Drug Class:
- Nature: Synthetic peptide hormone
- Drug Class: GnRH agonist (LHRH analog), hormonal therapy
🎯 Purpose / Indications:
- Prostate cancer (palliative treatment)
- Endometriosis
- Uterine fibroids
- Precocious puberty
- Breast cancer (hormone-responsive, off-label)
- Assisted reproductive therapy (ART) for ovulation control
✅ Advantages:
- Effectively suppresses sex hormone production
- Non-surgical alternative for hormone-dependent conditions
- Once-daily, monthly, 3-monthly, or 6-monthly formulations available
- Delays disease progression in hormone-sensitive cancers
📦 Common Packaging:
- Prefilled syringes or vials (injectable solution or depot suspension)
- Available in doses like 3.75 mg (monthly), 11.25 mg (3-month), 22.5 mg, or 45 mg (6-month)
⚠️ Patient Advice / Precautions:
- Initial hormone surge may worsen symptoms temporarily (tumor flare)
- Long-term use may lead to bone mineral loss—monitor BMD
- Use non-hormonal contraception during therapy (for women)
- Monitor for depression, mood changes, and cardiovascular risks
- Not to be used during pregnancy or lactation