Here is the detailed overview of Kanamycin Powder for Injection 750 mg, with icons:
💉 Kanamycin Powder for Injection 750 mg
🧪 Nature / Drug Class
🔹 Aminoglycoside antibiotic
🔹 Bactericidal – inhibits bacterial protein synthesis
🔹 Second-line anti-tuberculosis (TB) drug
🔹 Effective against aerobic gram-negative bacilli and Mycobacterium tuberculosis
🩺 Purpose / Indications
✅ Used for:
- 🦠 Multidrug-resistant tuberculosis (MDR-TB)
- 🏥 Nosocomial infections (when sensitivity confirmed)
- 💊 Part of DOTS-Plus and other resistant TB regimens
- Occasionally for urinary tract infections, bacteremia, or intra-abdominal infections
⚙️ Advantages
✔️ Useful in TB cases resistant to first-line drugs
✔️ Rapid bactericidal action
✔️ Works well in combination therapy
✔️ Long history of use and WHO inclusion for MDR-TB
📦 Common Packaging
📦 750 mg sterile powder in glass vial
💧 Requires reconstitution with sterile water
💉 For IM or slow IV injection
⚠️ Patient Advice / Precautions
🦻 Watch for hearing loss or dizziness (ototoxicity)
🧪 Periodic tests for:
- Renal function (creatinine clearance)
- Serum drug levels (if prolonged use)
- Audiometry (baseline & routine checks)
💧 Stay well-hydrated during therapy
⏱️ Typically given once daily in TB, adjust for renal function
🚫 Contraindications / Cautions
❌ Hypersensitivity to aminoglycosides
⚠️ Caution in:
- Patients with kidney disease
- Elderly or children (higher toxicity risk)
- Concurrent use of loop diuretics or other ototoxic drugs
- Neuromuscular disorders (e.g., myasthenia gravis)
🧊 Storage
🌡️ Store vial at 15–25°C (room temp)
💧 Use reconstituted solution immediately or refrigerate (2–8°C) and use within 24 hours
🚫 Protect from light & moisture