Here is the detailed, non-branded medical overview for:
💨 Ipratropium Respirator Solution for Nebulizer – 250 mcg/mL
✅ DESCRIPTION
Ipratropium is an anticholinergic bronchodilator used via nebulization to treat airway obstruction. It works by inhibiting muscarinic receptors in bronchial smooth muscle, leading to bronchodilation and improved airflow.
🧪 FORMULATION
- Strength: 250 micrograms per mL
- Form: Aqueous solution for inhalation via nebulizer
- Route: Inhalation only
- Usually supplied in unit-dose vials or multi-dose bottles
🌿 NATURE
- Antimuscarinic agent (quaternary ammonium derivative of atropine)
- Acts locally in the lungs with minimal systemic absorption
📌 USES
- Chronic Obstructive Pulmonary Disease (COPD)
- Acute bronchospasm
- Asthma (adjunct therapy)
- Chronic bronchitis / emphysema
- Used in nebulized form for patients unable to use MDI/DPI
🌟 ADVANTAGES
- Effective for quick relief of bronchospasm
- Can be used in combination with beta-agonists like salbutamol
- Preferred in elderly or very young patients who cannot coordinate inhaler use
- Minimal systemic side effects
⚠️ PRECAUTIONS
Monitor for:
- Dry mouth
- Cough or throat irritation
- Nausea, dizziness (rare)
- Blurred vision if solution gets into eyes
- Use with caution in:
- Glaucoma
- Urinary retention
- Prostate enlargement
❌ CONTRAINDICATIONS
- Known hypersensitivity to ipratropium or atropine derivatives
- Avoid contact with eyes — can cause pupil dilation and angle-closure glaucoma
🧊 STORAGE
- Store at 15–30°C (room temperature)
- Protect from light and freezing
- Use single-dose vial immediately after opening
- Keep out of reach of children
💡 ADMINISTRATION TIPS
- Use only with compressed-air nebulizer (not ultrasonic)
- Dose typically mixed with normal saline before nebulization
- Inhale calmly through mouthpiece or mask
- Clean nebulizer parts regularly to prevent contamination
- For combination use (e.g., with salbutamol), compatibility should be confirmed