Here is the complete information for Ipratropium Inhalation (MDI/DPI) 20 mcg/dose, without brand names:
๐จ Ipratropium Inhalation (MDI/DPI) โ 20 mcg/dose
โ DESCRIPTION
Ipratropium is a short-acting anticholinergic bronchodilator. It works by blocking muscarinic receptors in the airway, leading to bronchodilation and relief from airway obstruction. Commonly used for COPD and acute asthma exacerbations.
๐งช FORMULATION
- Each puff delivers: 20 micrograms of ipratropium bromide
- Available as:
- MDI (Metered Dose Inhaler)
- DPI (Dry Powder Inhaler)
- Route: Inhalation via mouth
๐ฟ NATURE
- Synthetic quaternary ammonium compound
- Antimuscarinic/anticholinergic agent
- Local action in lungs with minimal systemic absorption
๐ USES
- Chronic Obstructive Pulmonary Disease (COPD)
- Bronchial asthma (in combination therapy)
- Acute asthma attacks (with beta-agonists)
- Bronchospasm due to chronic bronchitis or emphysema
๐ ADVANTAGES
- Fast onset of action (within 15โ30 minutes)
- Minimal systemic side effects due to local action
- Can be used safely in cardiac patients
- Often used with beta-agonists (e.g., salbutamol) for synergistic effect
โ ๏ธ PRECAUTIONS
Possible Side Effects:
- Dry mouth
- Bitter taste
- Throat irritation
- Cough after inhalation
- Rarely: Urinary retention, glaucoma (with improper use)
Use with caution in:
- Narrow-angle glaucoma
- Prostatic hyperplasia
- Bladder obstruction
โ CONTRAINDICATIONS
- Known hypersensitivity to ipratropium or atropine derivatives
- Avoid spraying near eyes โ may worsen glaucoma
๐ง STORAGE
- Store below 30ยฐC
- Keep the inhaler cap closed when not in use
- Protect from direct sunlight and heat
- Do not puncture or incinerate the canister
๐ก ADMINISTRATION NOTES
- Shake well before each use (MDI)
- Inhale deeply while actuating the dose
- Rinse mouth after use to avoid dryness or irritation
- Clean inhaler mouthpiece regularly
- DPI: Use dry hands and do not exhale into device