Here is the detailed information for Hydrocortisone Powder for Injection – 200 mg (no brand names):
💉 Hydrocortisone Powder for Injection – 200 mg
✅ DESCRIPTION
Hydrocortisone is a synthetic glucocorticoid hormone used to treat conditions that require anti-inflammatory, anti-allergic, or immunosuppressive effects. The 200 mg injection form is commonly used in acute medical emergencies and severe inflammation.
🧪 FORMULATION
- Each vial contains:
- Hydrocortisone sodium succinate equivalent to 200 mg of hydrocortisone
- Dosage form: Sterile, lyophilized powder for injection
- Route: IV or IM
- Reconstitution: Mix with sterile water for injection or normal saline
🌿 NATURE
- Synthetic corticosteroid
- Mimics cortisol produced by adrenal glands
- Fast-acting, especially when given IV
📌 USES
- Adrenal crisis in patients with adrenal insufficiency
- Septic shock (as part of supportive care)
- Acute asthma or COPD exacerbations
- Severe allergic reactions
- Autoimmune flare-ups (e.g., SLE, RA)
- Cerebral edema
- Preoperative support in steroid-dependent patients
🌟 ADVANTAGES
- Rapid onset of action
- Effective in managing shock and inflammation
- Useful when oral steroid therapy is not possible
- Suitable for stress-dose steroid replacement
⚠️ PRECAUTIONS
Common Side Effects:
- Hyperglycemia
- Increased appetite
- Insomnia, mood swings
- Elevated blood pressure
- Electrolyte imbalance
Use with caution in:
- Diabetes mellitus
- Hypertension
- Osteoporosis
- Peptic ulcer disease
- Infections (unless used as part of treatment)
❌ CONTRAINDICATIONS
- Hypersensitivity to hydrocortisone
- Untreated systemic fungal infections
- Use cautiously in tuberculosis or viral infections
🧊 STORAGE
- Store below 25°C
- Protect from moisture and direct light
- After reconstitution:
- Use immediately or refrigerate
- Use within 24 hours if stored in a fridge
- Do not freeze the reconstituted solution
💡 ADMINISTRATION NOTES
- Administer slowly if via IV to avoid sudden cardiovascular effects
- Use sterile equipment and aseptic technique
- Monitor for infection signs and blood sugar in long-term or repeated doses
- Dosing depends on clinical severity and condition