Here is a complete overview of Hydrocortisone Powder for Injection 100 mg, without brand names:
💉 Hydrocortisone Powder for Injection – 100 mg
✅ DESCRIPTION
Hydrocortisone is a glucocorticoid (corticosteroid) used for its anti-inflammatory, immunosuppressive, and anti-allergic properties. The injectable form is a sterile lyophilized powder that is reconstituted before intravenous (IV) or intramuscular (IM) administration.
🧪 FORMULATION
- Each vial contains:
- Hydrocortisone sodium succinate equivalent to 100 mg hydrocortisone
- Form: Sterile powder for reconstitution
- Route: IV or IM injection
- Reconstitution: Use sterile water for injection or normal saline
🌿 NATURE
- Synthetic corticosteroid with effects similar to natural cortisol
- Anti-inflammatory, anti-stress, and immunosuppressive
- Rapid onset when given IV, making it suitable for emergencies
📌 USES
- Adrenal insufficiency (Addisonian crisis)
- Severe allergic reactions (anaphylaxis adjunct)
- Asthma exacerbations
- Septic shock
- Cerebral edema
- Autoimmune conditions (e.g., lupus, rheumatoid arthritis)
- Preoperative stress-dose steroid coverage in adrenal-impaired patients
🌟 ADVANTAGES
- Fast-acting in emergencies
- Broad spectrum use in critical care
- Reduces inflammation quickly
- Suitable for patients unable to take oral steroids
⚠️ PRECAUTIONS
Common Side Effects:
- Hyperglycemia
- Fluid retention, hypertension
- GI upset
- Mood changes
Long-term/High-Dose Risks:
- Immunosuppression
- Delayed wound healing
- Osteoporosis
- Adrenal suppression
Use with caution in:
- Diabetes, peptic ulcer, heart failure
- Pregnancy (only if clearly needed)
- Active infections (unless for immunosuppression)
❌ CONTRAINDICATIONS
- Systemic fungal infections
- Known hypersensitivity to hydrocortisone or any excipient
- Caution in viral infections (e.g., herpes, chickenpox)
🧊 STORAGE
- Store below 25°C
- Protect from light and moisture
- After reconstitution:
- Use immediately or store in refrigerator and use within 24 hours
- Do not freeze the reconstituted solution
💡 ADMINISTRATION TIPS
- Reconstitute with sterile water as per vial instructions
- Use aseptic technique
- Administer slowly if given IV (to avoid cardiac side effects)
- Monitor blood glucose, BP, and infection signs in long-term use