🔹 Human Chorionic Gonadotropin (hCG) Injection 5000 IU – As Licensed
📄 Description:
Human Chorionic Gonadotropin (hCG) is a hormonal medication that mimics the action of luteinizing hormone (LH). It is used in fertility treatments to trigger ovulation in women and stimulate testosterone production in men.
💊 Prescription / Use:
- Indications:
- Induction of ovulation in women with infertility
- Luteal phase support in IVF cycles
- Male hypogonadotropic hypogonadism
- Cryptorchidism (undescended testes in boys)
- Common Dose:
- Women (Ovulation induction): 5000–10,000 IU single IM or SC dose after follicular maturation
- Men (Hypogonadism): 1000–3000 IU IM 2–3 times weekly
- Dose may vary based on treatment protocol and patient response
- Route of Administration: Intramuscular (IM) or Subcutaneous (SC) injection
🔬 Nature:
- Hormonal class: Gonadotropin
- Mechanism of Action:
- Mimics LH surge to trigger ovulation
- Stimulates Leydig cells to produce testosterone
- Source: Human urinary hCG or recombinant technology
🌟 Advantages:
- Precisely triggers ovulation in assisted reproductive therapy (ART)
- Supports corpus luteum function post-ovulation
- Promotes testicular descent in children
- Improves spermatogenesis in men
📦 Packaging:
- Supplied as:
- 1 vial containing 5000 IU lyophilized powder
- 1 ampoule or vial of solvent (usually 1 mL of water for injection)
- Single-use packaging
- Comes in a sealed box with labeling including:
- Name, dosage (5000 IU), expiry, batch number, manufacturer
🧊 Storage:
- Store at 2°C to 8°C (refrigerated)
- Do not freeze
- Protect from direct light
- After reconstitution, use immediately and discard unused portion
⚠️ Precautions:
- Do not use if:
- Patient is already pregnant (unless prescribed for luteal support)
- Known allergy to hCG
- Hormone-dependent tumors (e.g., prostate cancer)
- Early puberty in boys
- Use with caution in:
- PCOS patients (risk of OHSS)
- Multiple follicle stimulation cycles
- Thromboembolic disorders
- Possible side effects:
- Ovarian Hyperstimulation Syndrome (OHSS) in women
- Headache, fatigue, irritability
- Gynecomastia, acne, water retention in men
- Local reaction at injection site
👩⚕️ Patient Advice:
- Administer exactly as scheduled by your doctor
- Do not self-inject unless trained
- For fertility use:
- Intercourse should be timed 24–36 hours after injection
- Report:
- Severe abdominal pain, bloating, shortness of breath (may indicate OHSS)
- In men, report:
- Testicular pain, swelling, or breast enlargement
- Dispose of needles/syringes safely if self-administering