Glucose Injection 5 %

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๐Ÿ’ง Glucose Injection 5% (Dextrose 5%)


โœ… DESCRIPTION

Glucose Injection 5% is a sterile, non-pyrogenic solution of dextrose (glucose) in water. It provides a source of calories and hydration when administered intravenously.


๐Ÿงช FORMULATION

  • Concentration: 5% w/v (i.e., 5 g of glucose per 100 mL)
  • Form: Injection/Infusion solution
  • Route: Intravenous (IV)
  • Available volumes: 100 mL, 250 mL, 500 mL, 1000 mL flexible or glass containers

๐ŸŒฟ NATURE

  • Crystalloid solution
  • Isotonic when infused (osmolarity ~252 mOsm/L)
  • Supplies both water and glucose

๐Ÿ“Œ USES

  • Fluid and electrolyte replenishment
  • Caloric support (short-term)
  • Vehicle for drug dilution/administration
  • Treatment of hypoglycemia (mild/moderate)
  • Post-operative hydration or when oral intake is not possible

๐ŸŒŸ ADVANTAGES

  • Provides energy (approx. 170 kcal/L)
  • Helps prevent ketosis during fasting
  • Can be combined with other IV medications
  • Compatible with many drugs and electrolytes

โš ๏ธ PRECAUTIONS

  • Monitor for hyperglycemia, especially in diabetic patients
  • Watch for fluid overload in patients with cardiac or renal dysfunction
  • Not suitable as the sole source of nutrition in long-term use
  • Use with caution in head trauma or stroke patients

โŒ CONTRAINDICATIONS

  • Intracranial or intraspinal hemorrhage
  • Severe dehydration with electrolyte imbalance
  • Uncontrolled diabetes mellitus
  • Known hypersensitivity to dextrose

๐Ÿ’ข SIDE EFFECTS

  • Local: Phlebitis, injection site irritation
  • Systemic:
    • Hyperglycemia
    • Hyponatremia (dilutional)
    • Pulmonary edema, fluid overload
    • Rarely: allergic reaction, anaphylaxis

๐Ÿ“ฅ PACKING

  • Plastic infusion bottles or flexible pouches
  • Sizes: typically 100 mL to 1000 mL
  • Some may have additive ports for drug admixture

๐ŸงŠ STORAGE

  • Store at room temperature (15โ€“25ยฐC)
  • Protect from excessive heat and light
  • Do not use if solution is discolored or contains particulate matter
  • Use immediately after opening

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