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💊 Doxycycline Oral Liquid 50 mg/5 mL (p)
📘 Description:
- Doxycycline oral liquid is a broad-spectrum tetracycline antibiotic formulation, offering 50 mg of doxycycline in every 5 mL.
- It is designed for pediatric use or for patients who have difficulty swallowing tablets or capsules.
- The suspension is usually a yellow to light brown liquid, sometimes flavored to improve palatability.
- It contains doxycycline hyclate or other doxycycline salts dissolved or suspended in a sweetened, buffered vehicle.
- Available under brands like Doryx, Vibramycin, or generic formulations in hospitals and pharmacies.
🌿 Nature:
- Doxycycline is a semi-synthetic tetracycline, effective against a wide range of gram-positive and gram-negative bacteria.
- It works by inhibiting protein synthesis through binding to the 30S ribosomal subunit.
- It has bacteriostatic activity, meaning it stops bacteria from multiplying.
- Doxycycline is lipid-soluble, allowing better tissue penetration, including the lungs and sinuses.
- The oral liquid form ensures more flexible dosing and better compliance in children.
✅ Advantages:
- Effective against respiratory, urinary, skin, and sexually transmitted infections.
- Well tolerated in pediatric populations when dosed correctly.
- Easier to administer than tablets in young children or patients with swallowing issues.
- Can be used for malaria prophylaxis in children over 8 years old.
- Useful in rickettsial infections, acne, and some zoonotic infections like leptospirosis.
🩺 Uses:
- Bacterial respiratory infections like bronchitis and pneumonia.
- Skin and soft tissue infections, including acne vulgaris.
- Rickettsial diseases like Rocky Mountain spotted fever and typhus.
- Malaria prophylaxis and treatment (in combination) in children over 8 years.
- Treatment of chlamydia, Lyme disease, leptospirosis, and cholera.
❄️ Storage:
- Store at 20–25°C (68–77°F); avoid refrigeration unless specified.
- Shake well before each use to ensure uniform dosing.
- Protect from light and excessive heat.
- Discard unused suspension within 14–21 days after reconstitution (check label).
- Keep tightly closed and out of reach of children.
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