💉 Diazepam Pediatric Injection 5 mg/mL
📌 1. Prescription / Indication:
Diazepam Injection 5 mg/mL is prescribed for:
- Acute seizures (status epilepticus)
- Severe anxiety episodes or agitation
- Muscle spasms (e.g., tetanus)
- Premedication for procedures/sedation
- Alcohol withdrawal symptoms (e.g., delirium tremens)
⚠️ It is used in emergencies and in hospital or clinical settings, especially in pediatric seizure control when oral/rectal routes are not feasible.
📄 2. Description:
- Form: Sterile injectable solution
- Strength: 5 mg Diazepam per 1 mL
- Route: IV (intravenous), IM (intramuscular), or rectal (off-label use in some settings)
- Color: Clear, colorless to pale yellow
- Prescription: Required (Controlled drug – Schedule H/IV)
🔬 3. Nature / Pharmacological Class:
- Class: Benzodiazepine
- Type: Anxiolytic, anticonvulsant, sedative, muscle relaxant
- Mechanism: Enhances GABA-A receptor activity → CNS depression → sedation, seizure control, and muscle relaxation
🌟 4. Advantages:
- Rapid onset of action (especially IV)
- Essential for life-threatening seizures
- Useful when oral administration is not possible
- Flexible: Can be given IV, IM, or rectally (in specific pediatric settings)
📦 5. Common Packaging:
| Container Type | Volume |
|---|---|
| Glass ampoules | 2 mL, 5 mL vials |
| Prefilled syringes (in emergency kits) | Optional in some brands |
🧊 6. Storage Guidelines:
- Store at 15–30°C
- Protect from light and freezing
- Use immediately after opening
- Discard unused portion
- Keep out of children’s reach
👩⚕️ 7. Patient Advice / Caregiver Notes:
- Should be administered only by trained personnel
- For seizures, IV route is preferred for immediate effect
- Can cause:
- Sedation
- Confusion
- Respiratory depression (monitor breathing closely)
- Inform the provider about:
- Allergy to diazepam or other benzodiazepines
- Liver, kidney, or respiratory issues
- Do not combine with alcohol or opioids
🎯 8. Purpose / Therapeutic Use:
- Emergency control of status epilepticus
- Acute management of muscle rigidity or spasm
- Severe agitation or anxiety in clinical settings
- Sedation before surgery or procedures
- Management of withdrawal symptoms
⚠️ 9. Warnings / Precautions:
- Risk of respiratory suppression—monitor vitals continuously
- Can cause dependence or withdrawal symptoms if used repeatedly
- Use caution in:
- Newborns or premature infants
- Patients with respiratory or hepatic dysfunction
- Not suitable for long-term treatment