Here is the detailed information for:
💊 Dexamethasone Tablet 2 mg
✅ DESCRIPTION
Dexamethasone is a potent, long-acting synthetic corticosteroid with strong anti-inflammatory and immunosuppressant effects. It is approximately 25–30 times more potent than cortisol and has minimal mineralocorticoid (salt-retaining) activity.
⚖️ COMPOSITION
- Each tablet contains:
- Dexamethasone 2 mg
- Excipients: q.s. (e.g., starch, lactose – varies by manufacturer)
📌 USES
Used to treat a wide variety of conditions, including:
- Severe inflammatory disorders (e.g., arthritis, lupus, colitis)
- Allergic conditions (e.g., asthma, angioedema)
- Autoimmune diseases
- Certain cancers (as part of chemotherapy protocols)
- Cerebral edema
- Adrenal insufficiency (as glucocorticoid replacement)
- Adjunct in severe infections (e.g., meningitis)
- Severe COVID-19 (hospitalized patients needing oxygen)
🌟 ADVANTAGES
- Potent anti-inflammatory action at low doses
- Long biological half-life (36–54 hours)
- Minimal water/salt retention — preferred in brain edema
- Useful in steroid-responsive conditions when other agents fail
⚠️ PRECAUTIONS
- Use with caution in patients with:
- Diabetes
- Hypertension
- Peptic ulcers
- Psychiatric illness
- Infections (e.g., TB, fungal)
- Avoid abrupt withdrawal after long-term use
- Risk of adrenal suppression, especially with prolonged dosing
- Use in pregnancy only if clearly needed
❌ SIDE EFFECTS
(More likely with high dose or long-term use)
- Hyperglycemia, fluid retention, hypertension
- Mood changes, insomnia, psychosis
- Weight gain, osteoporosis, muscle weakness
- Increased risk of infections
- Gastric ulcers
💊 DOSAGE & ADMINISTRATION
- Dose varies based on condition and severity
- Typical adult dosing range: 0.5 mg to 10 mg/day
- Divided doses may be used
- Tapering required after prolonged use to avoid adrenal crisis
📦 PACKING
- Supplied in blister strips or HDPE bottles
- Typical pack sizes: 10, 30, 100 tablets
🧊 STORAGE
- Store below 25°C
- Keep away from moisture and light
- Keep out of reach of children