Dexamethasone Injection 4 mg/mL

📌 Dexamethasone Injection 4 mg/mL – As Licensed


📄 Description:

Dexamethasone Injection 4 mg/mL is a sterile injectable corticosteroid preparation used for its potent anti-inflammatory and immunosuppressive properties. It is suitable for use in acute medical conditions requiring rapid intervention.


💊 Prescription/Use:

  • Indications:
    • Severe allergic reactions (e.g., anaphylaxis adjunct)
    • Shock, including septic or anaphylactic shock
    • Cerebral edema (brain swelling)
    • Severe asthma or COPD exacerbation
    • Preterm labor (to enhance fetal lung maturity)
    • Certain cancers (e.g., leukemia, lymphoma)
    • Post-operative nausea and vomiting (PONV)
    • COVID-19 (as per clinical protocols)
  • Dosage & Administration:
    • Dose: Varies depending on indication (typically 4–20 mg/dose)
    • Route: Intravenous (IV) or Intramuscular (IM)
    • Frequency: As directed by a healthcare professional
    • Use under strict medical supervision
  • Prescription status: Rx Only

🔬 Nature:

  • Class: Glucocorticoid / Corticosteroid
  • Form: Clear aqueous solution for injection
  • Strength: 4 mg/mL
  • Type: Synthetic steroid hormone
  • Mechanism: Suppresses inflammation, immune response, and edema

🌟 Advantages:

  • Fast onset of action in emergencies
  • Can be used IV or IM
  • Potent and long-acting anti-inflammatory effects
  • Reduces swelling in cerebral edema and inflammation in airway diseases
  • Essential drug in many acute care protocols (ICU, emergency, surgery)

📦 Common Packaging:

  • Supplied in 1 mL or 2 mL ampoules or vials (typically 4 mg/mL)
  • Each ampoule clearly labeled with concentration, batch number, and expiry date
  • May be packaged in boxes of 5 or 10 ampoules

🧊 Storage:

  • Store at 15°C to 25°C (room temperature)
  • Do not freeze
  • Keep in original container, protected from light and heat
  • Discard if the solution appears cloudy, discolored, or contains particles

⚠️ Precautions:

  • Avoid abrupt withdrawal after prolonged use — taper slowly
  • Use with caution in patients with:
    • Diabetes (may raise blood sugar)
    • Hypertension
    • Peptic ulcer disease
    • Infections (e.g., TB, fungal)
  • May cause fluid retention, electrolyte imbalance
  • Monitor for signs of adrenal suppression with long-term use
  • Can interact with vaccines, especially live vaccines

👩‍⚕️ Patient Advice:

  • Injection is given only under medical supervision
  • Inform doctor of any known allergies, diabetes, or infections
  • Report immediately if you experience swelling, difficulty breathing, or mood changes
  • Follow-up may require monitoring of blood pressure, blood sugar, or electrolyte levels
  • Notify the healthcare provider if on long-term steroid treatment or undergoing surgery

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