Here is the complete information for:
💊 Daclatasvir Tablet 60 mg
🧪 Composition:
- Daclatasvir dihydrochloride equivalent to Daclatasvir 60 mg
🌐 Therapeutic Class:
- Antiviral (Direct-Acting Antiviral – DAA)
- NS5A Inhibitor
- Used in Hepatitis C Virus (HCV) infection
✅ Indications / Uses:
- Treatment of Chronic Hepatitis C infection (all genotypes)
- In combination with other antivirals, such as:
- Sofosbuvir
- Ribavirin (in some cases)
- Effective for treatment-naive and treatment-experienced patients
⚖️ Dosage:
- Daclatasvir 60 mg once daily
- Used with:
- Sofosbuvir 400 mg once daily, with or without Ribavirin
- Duration: Usually 12 to 24 weeks depending on:
- HCV genotype
- Presence of cirrhosis
- Prior treatment response
⚠️ Precautions:
- Always use in combination (never as monotherapy)
- Dose adjustment may be needed with strong CYP3A4 inhibitors or inducers
- Monitor for:
- Liver function
- Viral load
- Pregnancy: Use effective contraception during and 5 weeks after treatment when used with Ribavirin
🚫 Contraindications:
- Hypersensitivity to Daclatasvir
- Co-administration with:
- Rifampin
- Carbamazepine
- Phenytoin
- St. John’s Wort (strong enzyme inducers)
💥 Common Side Effects (when combined with Sofosbuvir):
- Fatigue
- Headache
- Nausea
- Insomnia
- Anemia (when used with Ribavirin)
👩⚕️ Use in Special Populations:
- Pregnancy: Caution (esp. with Ribavirin)
- Breastfeeding: Not recommended (limited data)
- Renal/Hepatic Impairment: No dose adjustment for mild/moderate; use caution in severe hepatic disease
📦 Storage:
- Store below 30°C
- Protect from moisture and direct light