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💊 Cloxacillin Capsule 250 mg
📘 Description:
Cloxacillin is a semisynthetic penicillin antibiotic used to treat bacterial infections caused by penicillinase-producing (β-lactamase-positive) Staphylococcus species. The 250 mg capsule is an oral dosage form.
💊 Prescription / Indications:
Cloxacillin is prescribed for the treatment of:
- Skin and soft tissue infections (e.g., boils, abscesses, impetigo)
- Bone and joint infections (e.g., osteomyelitis)
- Respiratory tract infections
- Endocarditis (in some regimens)
- Wound infections and post-surgical infections
- Septicemia caused by staphylococci
🩺 Uses:
- Active against penicillinase-producing staphylococci
- Often used in methicillin-sensitive Staphylococcus aureus (MSSA) infections
- Used in both adults and children under medical supervision
🌿 Nature:
- Drug Class: β-lactam antibiotic (Penicillinase-resistant penicillin)
- Form: Hard gelatin capsule
- Route: Oral
- Mechanism of Action: Inhibits bacterial cell wall synthesis (bactericidal)
✅ Advantages:
- Resistant to β-lactamase enzymes
- Good absorption when taken on an empty stomach
- Well tolerated in most patients
- Useful in community- and hospital-acquired infections
- Oral administration avoids hospitalization in mild/moderate cases
⚠️ Precautions:
- Do not use in patients with penicillin or cephalosporin allergy
- Take on an empty stomach (1 hour before or 2 hours after meals) for best absorption
- May cause side effects like:
- Nausea, vomiting
- Rash or allergic reactions
- Diarrhea or antibiotic-associated colitis (rare)
- Monitor renal and liver function during prolonged therapy
- Use with caution in neonates and elderly
- Not effective against MRSA
📦 Common Packaging:
- Strip/blister packs of 10 capsules
- Each capsule contains Cloxacillin Sodium equivalent to 250 mg of Cloxacillin
❄️ Storage:
- Store below 25°C, protected from light and moisture
- Keep in the original packaging
- Keep out of reach of children
- Do not use after expiry date printed on pack