Clindamycin Capsule 300 mg

💊 Clindamycin Capsule 300 mg


📘 Description:

  1. Clindamycin 300 mg capsule is an oral lincosamide antibiotic, formulated as clindamycin hydrochloride equivalent to 300 mg of clindamycin base.
  2. The capsule is typically hard gelatin, containing a white to off-white powder.
  3. It is used to treat moderate to severe bacterial infections caused by susceptible strains.
  4. The drug acts systemically, absorbed well through the GI tract.
  5. Common trade names include Cleocin, Dalacin C, and Clindac.

🌿 Nature:

  1. Clindamycin is a bacteriostatic antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit.
  2. It has strong activity against gram-positive cocci (like Streptococcus and Staphylococcus) and anaerobes.
  3. It does not cover gram-negative aerobic bacteria.
  4. Clindamycin exhibits good tissue penetration, including skin, bones, and abscesses.
  5. It has a moderate half-life allowing multiple daily doses (typically every 6–8 hours).

Advantages:

  1. Provides excellent alternative for penicillin-allergic patients.
  2. Highly effective in treating bone infections, such as osteomyelitis.
  3. Used for skin and soft tissue infections, including MRSA in certain settings.
  4. Penetrates well into abscesses, even with necrotic tissue.
  5. Suitable for combination therapy in serious mixed infections (e.g., with gentamicin or metronidazole).

🩺 Uses:

  1. Severe skin and soft tissue infections, such as cellulitis, abscesses, and wound infections.
  2. Bone and joint infections including chronic osteomyelitis.
  3. Dental infections and periodontal abscesses.
  4. Intra-abdominal and pelvic infections, including PID and endometritis.
  5. Respiratory tract infections such as aspiration pneumonia caused by anaerobes.

❄️ Storage:

  1. Store at room temperature (15°C to 25°C) in a dry place.
  2. Protect from moisture, heat, and direct sunlight.
  3. Keep in original tightly closed packaging.
  4. Do not use beyond the expiry date on the label.
  5. Store out of reach of children and pets to avoid accidental ingestion.

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