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💊 Clindamycin Capsule 300 mg
📘 Description:
- Clindamycin 300 mg capsule is an oral lincosamide antibiotic, formulated as clindamycin hydrochloride equivalent to 300 mg of clindamycin base.
- The capsule is typically hard gelatin, containing a white to off-white powder.
- It is used to treat moderate to severe bacterial infections caused by susceptible strains.
- The drug acts systemically, absorbed well through the GI tract.
- Common trade names include Cleocin, Dalacin C, and Clindac.
🌿 Nature:
- Clindamycin is a bacteriostatic antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit.
- It has strong activity against gram-positive cocci (like Streptococcus and Staphylococcus) and anaerobes.
- It does not cover gram-negative aerobic bacteria.
- Clindamycin exhibits good tissue penetration, including skin, bones, and abscesses.
- It has a moderate half-life allowing multiple daily doses (typically every 6–8 hours).
✅ Advantages:
- Provides excellent alternative for penicillin-allergic patients.
- Highly effective in treating bone infections, such as osteomyelitis.
- Used for skin and soft tissue infections, including MRSA in certain settings.
- Penetrates well into abscesses, even with necrotic tissue.
- Suitable for combination therapy in serious mixed infections (e.g., with gentamicin or metronidazole).
🩺 Uses:
- Severe skin and soft tissue infections, such as cellulitis, abscesses, and wound infections.
- Bone and joint infections including chronic osteomyelitis.
- Dental infections and periodontal abscesses.
- Intra-abdominal and pelvic infections, including PID and endometritis.
- Respiratory tract infections such as aspiration pneumonia caused by anaerobes.
❄️ Storage:
- Store at room temperature (15°C to 25°C) in a dry place.
- Protect from moisture, heat, and direct sunlight.
- Keep in original tightly closed packaging.
- Do not use beyond the expiry date on the label.
- Store out of reach of children and pets to avoid accidental ingestion.
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