Clindamycin Capsule 150 mg

💊 Clindamycin Capsule 150 mg

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📘 Description:

1. Clindamycin is a lincosamide antibiotic derived from lincomycin, effective against gram-positive and anaerobic bacteria.
2. The 150 mg capsule is a solid oral dosage form containing clindamycin hydrochloride equivalent to 150 mg of clindamycin base.
3. It is typically white to off-white powder enclosed in a hard gelatin capsule.
4. Each capsule is designed for systemic absorption via the gastrointestinal tract.
5. Common brand names include Dalacin C, Cleocin, and Clincin.

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🌿 Nature:

1. It is a bacteriostatic agent that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit.
2. Clindamycin is active mainly against anaerobes, Staphylococcus aureus, and Streptococcus species.
3. It has good tissue penetration, including into bones and abscesses.
4. It is not active against gram-negative aerobes.
5. Cross-resistance with macrolide antibiotics can occur.

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✅ Advantages:

1. Effective in treating skin, soft tissue, and bone infections, especially in penicillin-allergic patients.
2. Excellent oral bioavailability, nearly equivalent to IV formulation.
3. Good penetration into bone and abscesses, making it ideal for osteomyelitis.
4. Effective against MRSA in certain community-acquired infections.
5. Can be used in combination therapy for severe infections like pelvic inflammatory disease.

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🩺 Uses:

1. Skin and soft tissue infections, including cellulitis and abscesses.
2. Osteomyelitis and septic arthritis due to Staphylococcus aureus.
3. Dental infections and prophylaxis in penicillin-allergic patients.
4. Anaerobic intra-abdominal infections (e.g., peritonitis).
5. Pelvic infections and bacterial vaginosis (often with other agents).

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❄️ Storage:

1. Store at room temperature (15°C to 25°C), away from excess moisture and heat.
2. Keep in the original blister pack or container, tightly closed.
3. Protect from direct sunlight and do not freeze.
4. Keep out of reach of children.
5. Do not use expired capsules, as potency may reduce and risk of side effects increases.

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