Here is the detailed information for:
💊 Clindamycin Capsule 150 mg
📘 Description:
Clindamycin is a lincosamide antibiotic available in capsule form, typically used to treat serious bacterial infections caused by susceptible anaerobic bacteria and some protozoa.
📄 Prescription / Indications:
Clindamycin 150 mg capsules are commonly prescribed for:
- Skin and soft tissue infections
- Bone and joint infections (e.g., osteomyelitis)
- Dental infections
- Pelvic inflammatory disease (PID)
- Respiratory tract infections (e.g., aspiration pneumonia)
- Malaria (in combination therapy)
- Toxoplasmosis (in immunocompromised patients)
🌿 Nature / Drug Class:
- Lincosamide antibiotic
- Bacteriostatic, but bactericidal at high concentrations
- Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit
✅ Advantages:
- Effective against anaerobic organisms
- Useful in penicillin-allergic patients
- Good tissue penetration, especially in bone
- Can be used in mixed infections involving aerobic and anaerobic organisms
⚠️ Precautions:
- Can cause Clostridioides difficile-associated diarrhea (including pseudomembranous colitis)
- Use cautiously in patients with history of gastrointestinal disease
- May cause liver enzyme elevations or hepatic dysfunction
- Monitor renal and liver function in prolonged therapy
- Not usually first-line for routine infections due to higher risk of GI adverse effects
📦 Common Packaging:
- Capsules containing 150 mg of clindamycin hydrochloride
- Often available in strips of 10 capsules or bottles of 100 capsules (hospital use)
❄️ Storage Conditions:
- Store at room temperature (15–25°C)
- Keep away from moisture and light
- Keep out of reach of children