Here is the complete profile for:
💊 Clarithromycin Tablet 500 mg
📘 Description:
Clarithromycin 500 mg is a macrolide antibiotic used for treating moderate to severe bacterial infections. It works by inhibiting bacterial protein synthesis, thereby stopping growth.
📄 Prescription / Indications:
Prescribed for treatment of:
- Community-acquired pneumonia
- Acute exacerbation of chronic bronchitis
- Pharyngitis / tonsillitis
- Sinusitis
- Skin and soft tissue infections
- Mycobacterial infections (e.g., MAC in HIV)
- Peptic ulcer disease (with omeprazole and amoxicillin for H. pylori eradication)
🌿 Nature / Drug Class:
- Macrolide antibiotic
- Bacteriostatic (bactericidal at higher concentrations)
- Active against many Gram-positive, some Gram-negative, and atypical organisms
✅ Advantages:
- Longer half-life than erythromycin (twice-daily dosing)
- Improved acid stability (better GI tolerance)
- Effective in atypical respiratory pathogens like Mycoplasma, Chlamydia, Legionella
- Useful in triple therapy for H. pylori infection
- Available in oral and injectable formulations
⚠️ Precautions:
- Use with caution in hepatic impairment
- May prolong QT interval—avoid in arrhythmias or when using QT-prolonging drugs
- Potential for drug interactions via CYP3A4 inhibition (e.g., statins, theophylline, carbamazepine)
- Avoid during pregnancy and lactation unless prescribed
- Monitor for GI disturbances, altered taste, and hepatic function
📦 Common Packaging:
- Typically in blister strips of 6, 10, or 14 tablets
- Each tablet contains 500 mg of Clarithromycin
❄️ Storage Conditions:
- Store below 25°C
- Protect from light and moisture
- Keep in original packaging
- Keep out of reach of children