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💊 Clarithromycin Tablet 250 mg
📘 Description:
Clarithromycin is a macrolide antibiotic available in 250 mg oral tablet form. It works by inhibiting bacterial protein synthesis through binding to the 50S ribosomal subunit, leading to bacteriostatic or bactericidal effects depending on concentration and organism.
📄 Prescription / Indications:
Used for the treatment of:
- Respiratory tract infections (pharyngitis, tonsillitis, sinusitis, bronchitis, pneumonia)
- Skin and soft tissue infections
- Otitis media
- Helicobacter pylori eradication (as part of combination therapy in peptic ulcer disease)
- Mycobacterial infections (including Mycobacterium avium complex in immunocompromised patients)
🌿 Nature / Drug Class:
- Antibiotic
- Macrolide class
- Bacteriostatic (mainly), bactericidal at higher concentrations
✅ Advantages:
- Broad-spectrum action against gram-positive, gram-negative, and atypical bacteria
- Better tissue penetration compared to erythromycin
- Effective in H. pylori eradication regimens
- Longer half-life allows twice-daily dosing
⚠️ Precautions:
- Use with caution in patients with liver or kidney impairment
- May cause QT prolongation → avoid in patients with arrhythmia history
- Can interact with many drugs (e.g., statins, anticoagulants, theophylline, carbamazepine)
- Avoid in pregnancy unless clearly needed
- Common side effects: nausea, diarrhea, abdominal pain, altered taste
📦 Common Packaging:
- Blister pack of 6, 10, or 14 tablets (250 mg each)
❄️ Storage Conditions:
- Store below 25°C in a dry place
- Protect from light and moisture
- Keep out of reach of children