Here’s the detailed profile for:
💊 Clarithromycin Oral Liquid 125 mg/5 mL (p)
📘 Description:
Clarithromycin is a macrolide antibiotic formulated as an oral suspension containing 125 mg per 5 mL. It works by binding to the 50S ribosomal subunit of bacteria, inhibiting protein synthesis and stopping bacterial growth.
This suspension is especially suitable for children and patients who cannot swallow tablets.
📄 Prescription / Indications:
Used for treatment of:
- Respiratory tract infections (pharyngitis, tonsillitis, sinusitis, bronchitis, pneumonia)
- Skin and soft tissue infections
- Otitis media (ear infections)
- Helicobacter pylori eradication (as part of combination therapy)
- Mycobacterial infections (including Mycobacterium avium complex) in immunocompromised patients
🌿 Nature / Drug Class:
- Antibiotic
- Macrolide class
- Bacteriostatic, may be bactericidal at high concentration
✅ Advantages:
- Child-friendly liquid formulation
- Broader antibacterial spectrum compared to erythromycin
- Effective against atypical bacteria (Mycoplasma, Chlamydia, Legionella)
- Useful in respiratory and ear infections in children
- Palatable oral suspension for easier administration
⚠️ Precautions:
- Dose adjustment may be needed in renal or hepatic impairment
- Avoid in patients with QT prolongation or heart rhythm disorders
- Drug interactions possible with statins, anticoagulants, theophylline, and anticonvulsants
- Use with caution in pregnancy and breastfeeding
- Side effects: diarrhea, abdominal pain, nausea, vomiting, headache, taste disturbance
📦 Common Packaging:
- Bottles of 30 mL, 50 mL, 60 mL, or 100 mL oral suspension
- Usually supplied with a measuring cup or dropper
❄️ Storage Conditions:
- Store below 25°C in a dry place
- Shake well before use
- Once reconstituted, use within the recommended period (often 7–14 days depending on manufacturer)
- Keep tightly closed and away from children