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💊 Clarithromycin Oral Liquid 125 mg/5 mL (p)
📘 Description:
Clarithromycin 125 mg/5 mL is a macrolide antibiotic oral suspension used primarily in pediatric patients to treat various bacterial infections by inhibiting protein synthesis in bacteria.
📄 Prescription / Indications:
Prescribed in children for treatment of:
- Pharyngitis and tonsillitis
- Acute otitis media
- Sinusitis
- Skin and soft tissue infections
- Community-acquired pneumonia
- Mycobacterium avium complex (MAC) infections in HIV-positive children
🌿 Nature / Drug Class:
- Macrolide antibiotic
- Bacteriostatic (bactericidal at high concentrations)
- Active against Gram-positive cocci, some Gram-negative bacteria, and atypical organisms
✅ Advantages:
- Pediatric-friendly liquid formulation
- Better taste than many other antibiotics
- Long half-life allows twice-daily dosing
- Effective against atypical pathogens
- Useful in penicillin-allergic patients
⚠️ Precautions:
- Use with caution in liver impairment
- May interact with other medications (e.g., theophylline, warfarin, carbamazepine)
- May prolong QT interval – caution in patients with cardiac issues
- Monitor for gastrointestinal side effects like diarrhea, nausea
- Not to be mixed with acidic juices (e.g., grapefruit, orange)
📦 Common Packaging:
- Dry powder in bottle, reconstituted with water to make oral suspension
- After reconstitution:
- Each 5 mL contains 125 mg of Clarithromycin
- Common pack sizes: 30 mL, 50 mL, or 60 mL
❄️ Storage Conditions:
- Before reconstitution: Store at room temperature (below 25°C)
- After reconstitution:
- Store in refrigerator (2–8°C) or as per manufacturer’s label
- Shake well before each use
- Discard after 7–14 days (refer to label instructions)