Here is the complete profile for:
💉 Ceftazidime Powder for Injection 250 mg
📘 Description:
Ceftazidime 250 mg is a third-generation cephalosporin antibiotic, provided as a sterile powder for intravenous (IV) or intramuscular (IM) administration. It is especially effective against Pseudomonas aeruginosa and other resistant Gram-negative bacteria.
💊 Prescription / Indications:
Used for treating moderate to severe bacterial infections, such as:
- Lower respiratory tract infections (e.g. pneumonia, bronchitis)
- Urinary tract infections
- Septicemia (bloodstream infections)
- Meningitis (especially caused by Gram-negative organisms)
- Intra-abdominal infections (with metronidazole)
- Bone and joint infections
- Skin and soft tissue infections
- Infections in immunocompromised patients (e.g. cancer, neutropenia)
🩺 Uses:
- Bactericidal agent effective against a wide range of Gram-negative bacteria
- Often used in hospital settings
- Especially valuable in ICU, oncology, and surgical wards
🌿 Nature:
- Class: Third-generation cephalosporin
- Form: Lyophilized powder
- Route: IV or IM injection
- Mechanism: Inhibits bacterial cell wall synthesis → bacterial death
✅ Advantages:
- Strong activity against Pseudomonas and Enterobacteriaceae
- Can be used in combination therapy (e.g. with aminoglycosides or metronidazole)
- Effective even in severe infections in immunocompromised patients
- Stable in a wide range of diluents for injection
⚠️ Precautions:
- Contraindicated in patients allergic to cephalosporins or β-lactams
- Caution in renal impairment—dose modification required
- May alter coagulation profile in some patients
- Monitor for superinfection or fungal overgrowth in long-term use
- Possible side effects: rash, diarrhea, injection site pain, rarely seizures in renal impairment
📦 Common Packaging:
- Supplied in glass vials with 250 mg sterile powder
- For single use only
- Typically used in hospitals or clinics; comes in bulk hospital packs or single packs
❄️ Storage:
- Store below 25°C, in a dry place
- Protect from light and moisture
- Use reconstituted solution immediately or as per labeling (may vary)
- Keep out of reach of children